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Albendazole is highly effective against cutaneous larva migrans but not against Giardia infection: results of an open pilot trial in travellers returning from the tropics



Albendazole is highly effective against cutaneous larva migrans but not against Giardia infection: results of an open pilot trial in travellers returning from the tropics



Transactions of the Royal Society of Tropical Medicine and Hygiene 87(6): 689



Of 20 patients with symptomatic intestinal giardiasis in Austria who were treated with albendazole (10 to 15 mg/kg daily for 3 days), only 2 were negative for Giardia in all 3 post-treatment faecal samples, and showed any clinical improvement. All infected patients were successfully treated with tinidazole (2 g in a single dose). The infections were acquired in India, Nepal, Africa, the Near East and Central America. 17 patients (mainly from the Caribbean and Sri Lanka) with cutaneous larva migrans were treated with albendazole (10 to 15 mg/kg daily for 3 or 7 days). All showed marked improvement of the skin lesions within a few days, and with one exception symptoms disappeared promptly within less than 2 weeks. A 2nd course of treatment was necessary for only one patient with bacterial superinfection.

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Accession: 002295919

Download citation: RISBibTeXText

PMID: 8296380

DOI: 10.1016/0035-9203(93)90296-3


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