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Bayesian inference in multipoint gene mapping


, : Bayesian inference in multipoint gene mapping. Annals of Human Genetics 57(1): 65-82

The problem of ordering and mapping genes on the basis of recombinant data and radiation hybrid data is formulated as a problem of Bayesian inference for an unknown permutation. The challenging computational problems posed by this approach are shown to be resolvable using Markov chain Monte Carlo methods.

Accession: 002308553

PMID: 8333730

DOI: 10.1111/j.1469-1809.1993.tb00887.x

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