+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Behavioral and biochemical effects of postnatal parathion exposure in the rat

, : Behavioral and biochemical effects of postnatal parathion exposure in the rat. Neurotoxicology & Teratology 10(3): 261-266

Preweanling rat pups were exposed daily to parathion (1.3 mg/kg or 1.9 mg/kg) or vehicle (corn oil) on postnatal days 5-20, a time period critical to development of behavioral and biochemical parameters of the cholinergic nervous system. The exposure resulted in dose-dependent reduction in acetylcholinesterase activity and muscarinic receptor binding in the cortex. During the preweanling period, there were no differences among the groups in most reflex measures, eye opening or incisor eruption. Postweanling behavioral assessment revealed small deficits in tests of spatial memory in both the T-maze and the radial arm maze. There were no differences in neuromuscular abilities or spontaneous activity measures. Thus, biochemical and behavioral deficits in cholinergic nervous system functioning occurred in the absence of severe signs of toxicity and in the absence of generalized nonspecific behavioral disturbances.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 002308822

PMID: 3211105

DOI: 10.1016/0892-0362(88)90026-8

Download PDF Full Text: Behavioral and biochemical effects of postnatal parathion exposure in the rat

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Brown, L.F.; Beck, J.D.; Rozier, R.G., 1994: Incidence of attachment loss in community-dwelling older adults. Since 1985, only four studies have been published that present at a on attachment loss in populations. The purpose of this study was to present the incidence of attachment loss over an 18-month period in a representative sample of community-dwelli...

S Alves, T.L.; Chauveau, O.; Eggers, L.; de Souza-Chies, T.T., 2015: Species discrimination in Sisyrinchium (Iridaceae): assessment of DNA barcodes in a taxonomically challenging genus. DNA barcoding aims to develop an efficient tool for species identification based on short and standardized DNA sequences. In this study, the DNA barcode paradigm was tested among the genera of the tribe Sisyrinchieae (Iridoideae). Sisyrinchium, wi...

Kadowaki, T.; Yamauchi, T.; Okada-Iwabu, M.; Iwabu, M., 2015: Adiponectin and its receptors: implications for obesity-associated diseases and longevity. Lancet. Diabetes & Endocrinology 2(1): 8-9

Muench, A., 1973: Specific heat of dental restorative materials, enamel and dentin. Revista Da Faculdade de Odontologia Da Universidade de Sao Paulo 11(1): 29-35

Wrona, A.F.; Ball, S.T.; Glover, C.; Banks, J.C.; Burmester, C.H.; Monks, C.D.; Brown, S.M.; Edmisten, K.; Hake, K.; Lege, K.; Lemon, R.; Stichler, C.; Warrick, B.; Maitland, J.; Mayfield, W.; McCarty, W.; Padgett, B.; Phipps, B.; Robertson, B.; Shelby, P.; Silvertooth, J.C.; Vargas, R.; Wright, D.L., 1997: The 1996 production year. Cotton production conditions in Arizona, California, New Mexico, Oklahoma, Texas, Arkansas, Louisiana, Missouri, Mississippi, Tennessee, Alabama, Florida, Georgia, North Carolina, South Carolina and Virginia are briefly described. Some data on cro...

Laviron, P. A., 1964: Massive campaigns and their difficulties in anti-leprous fight in Dark Africa. Difficulties of most massive anti-leprous campaigns in Africa consist of the lack of mobility of the service in charge, irregular pattern of the visits and lack of qualified medical help in the field. Sulfones are an excellent elastic medication,...

Guilhermet R.; Mathieu C.M.; Toullec R., 1975: Transit of liquid food through the esophageal groove in the preruminant and ruminant calf. Annales de Zootechnie (Paris) 24(1): 69-80

Williams, C.L.; Westermeyer, J., 1985: Public health aspects of mental health: the last 75 years of the American Journal of Public Health. The American Journal of Public Health has reflected the relationship of public health to the field of mental health over its 75-year history. The earliest volumes of the Journal addressed movements and concerns within public mental health. Quantit...

Kleine, R., 1926: On the Dependence of Oscinella frit on Temperature. The author's observations on the dependence of insects on temperature and on the correlation between it and the appearance of a given species have already been discussed . Two series of observations, one at Stettin and the other at Warsow abo...

Martin, J.W.; Vetter, E.W.; Cash Clark, C.E., 1996: Description, external morphology, and natural history observations of Nebalia hessleri, new species , from southern California, with a key to the extant families and genera of the Leptostraca. A new and relatively large species of leptostracan crustacean, Nebalia hessleri, is described from enriched sediments and detrital mats off southern California. The new species is characterized by its size, possession of "normal" (versus...