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Behaviour in mice of a strain of Leishmania mexicana isolated from a case of diffuse cutaneous leishmaniasis

, : Behaviour in mice of a strain of Leishmania mexicana isolated from a case of diffuse cutaneous leishmaniasis. Revista Latinoamericana de Microbiologia 32(4): 307-313

BALB/c and C57BL/6 strains of mice were inoculated with several doses of promastigotes of a Leishmania mexicana strain isolated from a DCL patient. The C57BL/6 mice developed a localized skin lesion which healed spontaneously. BALB/c mice were unable to control the infection, developing diffuse cutaneous lesions with ulceration. In both strains of mice the granuloma was formed of numerous macrophages, eosinophils, and plasma cells.

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