+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Butyrophilin and xanthine oxidase occur in constant molar proportions in milk lipid globule membrane but vary in amount with breed and stage of lactation



Butyrophilin and xanthine oxidase occur in constant molar proportions in milk lipid globule membrane but vary in amount with breed and stage of lactation



Protoplasma 177(1-2): 32-36



Butyrophilin and xanthine oxidase, major proteins of milk lipid globule membrane, both accounted for significantly higher percentages of total protein in membrane samples from Holstein than from Jersey animals. Both were high in membranes from animals in early lactation, both decreased in amount as lactation progressed to the midpoint, and then both rose in amount toward the end of lactation. In samples from both Holstein and Jersey animals, butyrophilin and xanthine oxidase were present in constant molar proportions of about 4:1. These proteins co-enriched together with low molecular weight GTP-binding proteins in a high salt and nonionic detergent insoluble fraction of milk lipid globule membrane. Butyrophilin and xanthine oxidase content of membranes was not related to milk lipid globule diameter, suggesting that these proteins alone may not be involved solely in anchoring the membrane to the lipid globule surface. However, the possibility that a complex composed in part of butyrophilin and xanthine oxidase serves an anchoring function remains a possibility.

(PDF emailed within 0-6 h: $19.90)

Accession: 002314511

Download citation: RISBibTeXText

DOI: 10.1007/bf01403396



Related references

Butyrophilin of milk lipid globule membrane contains N-linked carbohydrates and cross-links with xanthine oxidase. International journal of biochemistry1(1): 103-107, 1988

Butyrophilin of milk lipid globule membrane contains N-linked carbohydrates and cross-links with xanthine oxidase. International Journal of Biochemistry 21(1): 103-107, 1989

Xanthine oxidase of bovine milk fat globule membrane is associated with lipid per oxidation and cytochrome b 5 reduction. European Journal of Cell Biology 22(1): 271, 1980

Interaction of cytoplasmic domain of bytyrophilin with xanthine oxidase Potential mechanism for the formation of milk-fat-globule membrane during milk-lipid secretion. Molecular Biology of the Cell 13(Supplement): 136a, 2002

Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein. Biochimica et Biophysica Acta 1334(2-3): 182-190, 1997

Topology of mouse butyrophilin and xanthine dehydrogenase/oxidase in milk-lipid droplets Potential interaction via the B302 domain. FASEB Journal 15(5): A895, March 8, 2001

Cloning and analysis of complementary dna encoding bovine butyrophilin an apical glycoprotein expressed in mammary tissue and secreted in association with the milk fat globule membrane during lactation. Journal of Biological Chemistry 265(24): 14481-14486, 1990

Cloning and analysis of cDNA encoding bovine butyrophilin, an apical glycoprotein expressed in mammary tissue and secreted in association with the milk-fat globule membrane during lactation. Journal of Biological Chemistry 265(24): 14481-6, 1990

Compositional homology of membrane-protein systems and membrane-associated proteins: comparison with milk fat globule membrane and "membrane"-derived xanthine oxidase. Journal of Dairy Science 60(8): 1208-1216, 1977

Isolation and partial characterization of xanthine oxidase associated with the milk fat globule membrane of cows milk. Journal of Dairy Science 60(6): 841-850, 1977

The fat-globule membrane of milk: alkaline phosphatase and xanthine oxidase in skim-milk and cream. J. Dairy Sci, 39: 5, 528-35, 1956

Association of xanthine oxidase with the bovine milk-fat-globule membrane. Biochemical Journal 143(1): 149-157, 1974

Solubilization and purification of xanthine oxidase from bovine milk fat globule membrane. Protein Expression and Purification 13(2): 229-234, 1998

Purification of xanthine oxidase from the fat-globule membrane of bovine milk by electrofocusing. Molecular and Cellular Biochemistry 44(1): 13-22, 1982