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Comparison of intramuscular irritation caused by two formulations of oxytetracycline LA

Comparison of intramuscular irritation caused by two formulations of oxytetracycline LA

Medicina Veterinaria 9(12): 710-723

ISSN/ISBN: 0212-8292

Two groups of 6 cattle were injected i.m. with either Coopermycin LA (Pitman-Moore) or Terramycin LA (Pfizer). In each group, 3 animals were given a single dose and 3 a double dose. Injection of oxytetracycline led to an increase in serum creatine kinase (CK) glutamic-oxaloacetic transminase and sorbitol dehydrogenase. The increase was greater in Terramycin-injected animals, significantly so for CK. In the muscles, activity of CK was decreased and activity of lysozyme was increased.

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