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Effect of fluconazole on the interactions between human neutrophils and Candida albicans


, : Effect of fluconazole on the interactions between human neutrophils and Candida albicans. International Journal of Antimicrobial Agents 3(3): 171-173

The effects of fluconazole on the candidacidal activity of human neutrophils were investigated. Three clinical isolates of Candida albicans were studied in a colony count assay and the presence of fluconazole during incubation of yeasts with neutrophils had no effect on neutrophil candidacidal activity. These results, using a different assay and three additional isolates, confirm previous studies showing that fluconazole does not interfere with the ability of neutrophils to kill C. albicans.

Accession: 002355875

PMID: 18611558

DOI: 10.1016/0924-8579(93)90010-3

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