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Effect of fluconazole on the interactions between human neutrophils and Candida albicans

International Journal of Antimicrobial Agents 3(3): 171-173

Effect of fluconazole on the interactions between human neutrophils and Candida albicans

The effects of fluconazole on the candidacidal activity of human neutrophils were investigated. Three clinical isolates of Candida albicans were studied in a colony count assay and the presence of fluconazole during incubation of yeasts with neutrophils had no effect on neutrophil candidacidal activity. These results, using a different assay and three additional isolates, confirm previous studies showing that fluconazole does not interfere with the ability of neutrophils to kill C. albicans.

Accession: 002355875

PMID: 18611558

DOI: 10.1016/0924-8579(93)90010-3

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