EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of food restriction on hyperoxia-induced lung injury in preterm guinea pig


, : Effect of food restriction on hyperoxia-induced lung injury in preterm guinea pig. American Journal of Physiology 263(3 Pt 1): L357-L362

Undernutrition may exacerbate hyperoxia-induced lung injury, a finding that may be of significance in the early clinical management of the premature human infant. Addressing this specific problem, we found that 72 h of food restriction in guinea pig pups delivered 3 days preterm increased mortality rates among pups exposed to 95% oxygen (8/18) and yet had no effect on 21% oxygen (air)-exposed pups (0/10). Reduced tolerance of hyperoxic conditions was not, however, associated with increased lung injury, assessed as pulmonary microvascular leakage. Pulmonary antioxidant enzyme activities [Cu,Zn superoxide dismutase (SOD), Mn SOD, glutathione peroxidase, and catalase] were unaltered by starvation or hyperoxia. Lung glutathione concentration was slightly decreased after food restriction, whereas hyperoxic exposure did not change either lung or bronchoalveolar lavage fluid glutathione concentrations or lung antioxidant enzyme activities. Increased susceptibility to the lethal effects of oxygen in the starved preterm guinea pig pup could not be attributed to a deficiency of pulmonary antioxidant defenses.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 002355964

PMID: 1415561

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Covert, Sf; Enkerli, J; Miao, Vpw; Vanetten, Hd, 1996: A gene for maackiain detoxification from a dispensible chromosome of Nectria haematococca. In Nectria haematococca the MAK1 gene product converts a chick-pea (Cicer arietinum) phytoalexin, maackiain, into a less toxic compound. The presence of MAK1 in this fungal pathogen is also correlated with high virulence on chick-pea. Previous gen...

Kumpuris, A.G.; Luchi, R.J.; Waddell, C.C.; Miller, R.R., 1980: Production of circulating platelet aggregates by exercise in coronary patients. To determine the effect of exercise on the in vivo formation of circulating platelet aggregates in patients with severe coronary artery disease (CAD), platelet aggregate ratios (PAR) (normal 0.8-1.1) were measured immediately before and after trea...

Xavier Andrea Gallo; Vinzon Susana Beatriz, 1998: Suspended sediment effects on the Amazon Shelf hydrodynamics. Eos, Transactions, American Geophysical Union 79(45, Suppl

Littman, L.; Glatt, B. S.; Pritchett, D. B.; Robinson, M. B., 1993: Differentiation of metabotropic receptors using L-aspartate-beta-hydroxamate. Society for Neuroscience Abstracts 19(1-3): 471

Heimfeld, Shelly; Bode, Hans R., 1986: Growth regulation of the interstitial cell population in hydra. Control of nerve cell and nematocyte differentiation by amplification of non-stem interstitial cells. Developmental Biology 116: 68

Hijimoto, S.; Itani, T., 1975: Studies on ecological characteristics of solidago altissima part 1 effects of soil moisture nutrient elements and shading on the growth. Golden rod, S. altissima, seedlings propagated by cutting were studied for about 3 mo. Optimum water holding capacity for growth was 50%-70%. The seedlings grew normally even at severe conditions, i.e., at 30% and 90%. Among the nutrients applied...

Prado, I.M.; Miglino, M.A.; DiDio, L.J., 1997: Morphology of the swine ileum terminale. The morphology of the terminal ileum was studied in 33 male adult pigs of unknown breed. The ileum ended in the cecocolic junction at an acute angle to the cecum. The terminal ileum displayed a cylindrical form (63.6% +/- 8.4 of the cases) more fr...

Singh, R. P., 1980: Association of grain yield and its components in F1 and F2 populations of rice. Correlation analysis of data from segregating and nonsegregating populations from a 6 X 6 diallel, excluding reciprocals, revealed that grain yield per plant was positively correlated with (1) number of fertile tillers, (2) grain weight and (3) nu...

Moreno Gomez, F.; Munoz Rodriguez, M.; Morea Roy, J., 1999: Sunflower methyl ester as a fuel for automobile diesel engines. This article presents the results of an investigation carried out in an automobile diesel engine running on sunflower oil methyl ester (SME), pure and mixed with diesel fuel. Engine test bench studies have been carried out, with the aim of obtaini...

Watters, D.A.; Sinclair, J.R.; Luo, N.; Verma, R., 1988: HIV seroprevalence in critically ill patients in Zambia. Of 396 patients admitted to the intensive care unit of the University Teaching Hospital, Lusaka, between January 1986 and January 1987, 43 (17.9%) of 240 males were seropositive and 38 (24.3%) of 156 females were seropositive (not a significant di...