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Efficacy of a g III-/TK- modified live Aujeszky's disease virus vaccine against experimental dual infection with Aujeszky virus and Actinobacillus pleuropneumoniae in pigs


, : Efficacy of a g III-/TK- modified live Aujeszky's disease virus vaccine against experimental dual infection with Aujeszky virus and Actinobacillus pleuropneumoniae in pigs. Journal of the Japan Veterinary Medical Association 46(3): 210-213

An attenuated Aujeszky virus vaccine with deletions in the thymidine kinase and glycoprotein g III genes was administered to four 4-week-old SPF pigs. There were 4 unvaccinated controls. All pigs were challenged intranasally with Aujeszky virus (106.0 TC1D50/pig) and serotype 1 A. pleuropneumoniae (106.2 CFU/pig) at 7 and 8 weeks of age, respectively.


Accession: 002367393

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Related references

Sakano, T.; Shibata, I.; Samegai, Y.; Taneda, A.; Okada, M.; Irisawa, T.; Sato, S., 1993: Experimental pneumonia of pigs infected with Aujeszky's disease virus and Actinobacillus pleuropneumoniae. Intranasal inoculation of Aujeszky virus (ADV, 106.9 median tissue culture infective dose/head) in 4-month-old primary SPF pigs was followed by the inoculation of A. pleuropneumoniae type 1 (103.1 or 105.1 colony-forming-units/head). The pigs inoc...

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