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Efficacy of a non-steroidal anti-inflammatory, ketogen 10% (ketoprofen) in the treatment of colic in horses

, : Efficacy of a non-steroidal anti-inflammatory, ketogen 10% (ketoprofen) in the treatment of colic in horses. Journal of Equine Veterinary Science 12(5): 311-315

In a multi-site clinical trial ketoprofen used i.v. at a dose-rate of 2 mg/kg of body weight showed a potent analgesic effect in the management of pain in 67 horses affected by colic. Clinical examinations were conducted for 8 h after treatment, including evaluation of attitude of the animal pain, characteristics of pulse, colour of mucosa, sweating, rectal temperature, heart and respiratory rates. One hour after initiation of therapy, there was a significant improvement of these symptoms.

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Related references

Longo, F.A.tefage, A.B.yle, R.K.ister, M.G.ol, F.V.n, 1992: Efficacy of a non-steroidal anti-inflammatory, Ketofen 10% (Ketoprofen) in the treatment of colic in horses. Journal of equine veterinary science 12(5): 311-315

Longo, F.; Autefage, A.; Bayle, R.; Gool, F. van, 1990: Efficacy of ketoprofen in the treatment of colic in horses. A trial of ketoprofen at a dose of 2 mg/kg i.v. in 67 horses with different types of colic in nine veterinary practices gave results judged to be excellent in 89.5% of cases, good in 9% and fair in 1.5%; 48 cases needed only one dose, 15 two, and...

Holdgate, A.; Pollock, T., 2004: Systematic review of the relative efficacy of non-steroidal anti-inflammatory drugs and opioids in the treatment of acute renal colic. Objective To examine the relative benefits and disadvantages of non-steroidal anti-inflammatory drugs (NSAIDs) mid opioids for the management of acute renal colic. Data sources Cochrane Renal Group's specialised register, Cochrane central reg...

Archimbaud J.P.; Medecins S.L., 1981: Treatment of nephritic colic by a nonsteroidal anti inflammatory ketoprofen. Attacks of nephritic colic (192) were observed within 3 mo. by the SOS Lyon Medecins organization. In 189 cases the following protocol was observed; patients were placed under an absolute hydric restriction and were given: an analgesic drug suited...

Hurault de Ligny, B.; Ryckelynck, J.P., 1989: The role of non steroidal anti-inflammatory agents in the treatment of renal colic. Nephrologie 10(1): 1-3

Guyonnet, J.C.; Julou, L., 1983: Relation between the inhibitory effect on the synthesis of the rabbit aorta contracting substance and prostaglandins and the anti-inflammatory activity of ketoprofen and other non-steroidal anti-inflammatory agents. This study showed that, relative to the other antiinflammatory drugs studied, ketoprofen is a stronger inhibitor of the synthesis of prostaglandins and Rabbit aorta Contracting Substance ("RCS") by guinea pig lung tissue in vitro. Althou...

Fournier, A.; Madassi, R., 1989: Risk of anuria during the use of non-steroidal anti-inflammatory agents in the treatment of nephritic colic of the only functional kidney. Nephrologie 10(4): 214-214

Guyonnet, J.C.; Julou, L., 1976: Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents. In this study ketoprofen has been shown to be the most potent of all anti-inflammatory drugs in inhibiting the synthesis of prostaglandins and the 'rabbit-aorta contracting substance' (RCS), using the guinea-pig lung preparation. Althoug...

Chowdhury, B.; Mukhopadhyay, S., 1997: Ketoprofen, a non-steroidal, anti-inflammatory drug, has antimicrobial activity against dermatophytes. The effect of ketoprofen on growth in vitro of eight fungal species and Candida albicans was tested. Ketoprofen showed significant antifungal activity against dermatophytes. The activity was affected by pH, being greater at values below pH 7.0. In...

Knoedler, J.J.; Lieske, J.C., 2016: Non-steroidal anti-inflammatory drugs for renal colic. Lancet 387(10032): 1971-1972