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Efficacy of moxidectin against gastrointestinal nematode infections in sheep

, : Efficacy of moxidectin against gastrointestinal nematode infections in sheep. Veterinary Parasitology 51(3-4): 301-305

The efficacy of moxidectin against gastrointestinal nematode infections was studied in 30 Fleischschaf times Rasa Aragonesa male lambs aged 3 months at the beginning of the experiment. The lambs were distributed in three groups of 10 animals each and experimentally infected with a mixture of an equal number of infective (L-3) larvae from each of the following species: Haemonchus contortus (2000), Ostertagia circumcincta (2000), Trichostrongylus colubriformis (2000) and Trichostrongylus vitrinus (2000). Two groups of lambs were drenched with 0.2 mg moxidectin per kg body weight at 6 (Group B) and 21 (Group C) days post challenge while the third group of animals (Group A) remained untreated. The efficacy of the treatment based on worm counts 4 weeks post infection was of 100% against 4th stage larvae of all species and 100%, 99.98%, 100% and 100% against adults of H. contortus, O. circumcincta, T. colubriformis and T. vitrinus, respectively. Significant differences were found in daily weight gain between treated (Group B+C, 157.9 g day-11) and untreated lambs (Group A, 116 g day-1). No differences in feeding behaviour or health condition between treated and untreated lambs were observed.

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Accession: 002367689

PMID: 8171833

DOI: 10.1016/0304-4017(94)90168-6

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