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Glucantime resistant Leishmania promastigotes are sensitive to pentostam

Moreira, E.S.; Guerra, J.B.; Petrillo-Peixoto, M.de.L.

Revista Da Sociedade Brasileira de Medicina Tropical 25(4): 247-250

1992


ISSN/ISBN: 0037-8682
PMID: 1340539
DOI: 10.1590/s0037-86821992000400006
Accession: 002393247

One glucantime sensitive strain (Leishmania braziliensis MHOM/BR/75/M2903), 3 naturally glucantime-resistant strains (L. braziliensis MHOM/BR/??/LTB259, L. braziliensis ISQN/BR/85/M9947 and L. amazonensis IFLA/BR/86/M10995) and one glucantime resistant line developed by in vitro drug exposure (line R2-1 derived from L. guyanensis IUMB/BR/85/M9945) were all found to be sensitive to pentostam (sodium stibogluconate) in vitro.

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