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Intracellular mechanisms involving gonadotropin and growth hormone release in the goldfish, Carassius auratus


, : Intracellular mechanisms involving gonadotropin and growth hormone release in the goldfish, Carassius auratus. Fish Physiology and Biochemistry 11(1-6): 25-33

Evidence for the involvement of Ca2+, protein kinase C, cAMP and arachidonic acid metabolism in the mediation of gonadotropin (GTH) and growth hormone (GH) release in the goldfish is reviewed, and models for the signal transduction pathway mediating GnRH and dopamine actions on GTH and GH secretion are postulated. A novel hypothesis, suggesting that two GnRHs which bind to the same receptor type activate different transduction cascades in 2 different cell types (GTH vs.

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