+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Intragastric tryptophan reduces glycemia after glucose, possibly via glucose-mediated insulinotropic polypeptide, in early-weaned piglets

, : Intragastric tryptophan reduces glycemia after glucose, possibly via glucose-mediated insulinotropic polypeptide, in early-weaned piglets. Journal of Nutrition 124(2): 259-267

The aim of this experiment was to investigate the influence of oral tryptophan on insulin, glucose-mediated insulinotropic polypeptide and glucose concentrations in early-weaned piglets. Piglets were given by intragastric infusion, at the same level of feeding, either a tryptophan-deficient or tryptophan-adequate diet for 22 d. During the experiment blood samples were taken after intragastric infusion of 1) the accustomed meal, 2) a glucose plus tryptophan load and 3) a glucose load. Plasma samples were analyzed for insulin, glucose-mediated insulinotropic polypeptide, glucose and lactate. After the accustomed meal plasma insulin concentrations were augmented and liquid gastric emptying faster in pigs fed tryptophan-adequate compared with tryptophan-deficient diets (P < 0.05) but glucose-mediated insulinotropic polypeptide, glucose and lactate were unaffected. The addition of tryptophan to a glucose load increased glucose-mediated insulinotropic polypeptide and reduced glucose in both tryptophan-adequate and tryptophan-deficient diet fed pigs (P < 0.05). Piglets adapted to the tryptophan-adequate diet had a greater glucose-mediated insulinotropic polypeptide response to intragastric glucose plus tryptophan than piglets adapted to the tryptophan-deficient diet. Adaptation to a tryptophan-adequate diet seems to increase the release of glucose-mediated insulinotropic polypeptide due to infusion of a tryptophan-adequate compared with a tryptophan-deficient diet. The addition of tryptophan to a glucose load reduces the level of glycemia, possibly through glucose-mediated insulinotropic polypeptide-mediated glucose disposal.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 002416145

PMID: 8308575

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Müller, R.; van Pée, K.H.; Eberspächer, J.; Lingens, F., 1992: Future developments in research on biological production and degradation of halogenated compounds. Biotransformations have gained extensive importance in practical use as a support for chemical synthesis or in the conversion of natural products. Biotransformations may present an enlargement, a sequential degradation or a specific modification o...

Gramlich, J. V.; Davis, D. E.; Funder-Burk, H. H., 1965: The effect of atrazine on nitrogen metabolism of resistant and susceptible plants. The following were carried out: (1) field experiments in which maize and S. halepense were sown in Norfolk sandy loam soil and sprayed pre-em. with atrazine, (2) growth-chamber experiments in which maize was planted in flats of loamy fine sand and...

Makarova, Ng, 1972: New species of Halacarina (acarina) from the litoral zone of the Kuril islands. Zoologicheskii zhurnal: 51 (8) 1241-1244

Yampol'skaya G.I., 1972: Familial neuro fibromatosis with unusual clinical features. Zhurnal Nevropatologii i Psikhiatrii Imeni S S Korsakova 72(6): 841-846

Roth D.A.; Mckay R.A.; Gelzer R.; Mckirnan M.D.; Bloor C.M.; Hammond H.K., 1992: Altered signal transduction after chronic episodic ischemia in porcine ventricle. FASEB Journal 6(4): A943

Wang, H-Bo.; Liu, G-Hong.; Zhang, H.; Xing, S.; Hu, L-Juan.; Zhao, W-Feng.; Xie, B.; Li, M-Zhi.; Zeng, B-Hang.; Li, Y.; Zeng, M-Sheng., 2013: Sp1 and c-Myc regulate transcription of BMI1 in nasopharyngeal carcinoma. B-lymphoma mouse Moloney leukemia virus insertion region 1 (Bmi1), a member of the polycomb group, has elevated expression and is involved in the pathogenesis of various aggressive cancers, including nasopharyngeal carcinoma (NPC). To date, the me...

Lewin H.A.; Bernoco D., 1986: Evidence for bovine lymphocyte antigen linked resistance to subclinical progression of bovine leukemia virus. Federation Proceedings 45(3): 491

Tamakoshi, K.; Yatsuya, H.; Wakai, K.; Suzuki, S.; Nishio, K.; Lin, Y.; Niwa, Y.; Kondo, T.; Yamamoto, A.; Tokudome, S.; Toyoshima, H.; Tamakoshi, A., 2005: Impact of menstrual and reproductive factors on breast cancer risk in Japan: results of the JACC study. The incidence of breast cancer among Japanese women, a traditionally low-risk population, has increased substantially. To evaluate the association of reproductive factors with breast cancer risk, we examined 38 159 Japanese women, aged 40-79 years...

Vamvoukakis J.A., 1988: Phoenix theophrasti on crete greece. Principes 32(2): 82-83

Barr Sandra M.; White Chris E., 1988: Petrochemistry of contrasting late Precambrian volcanic and plutonic associations, Caledonian Highlands, southern New Brunswick. Maritime Sediments and Atlantic Geology 24(3): 353-372