EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Intraindividual variation in serum cholesterol. What is the true value and when can a change be considered significant?






Nederlands Tijdschrift voor Geneeskunde 136(31): 1507-1511

Intraindividual variation in serum cholesterol. What is the true value and when can a change be considered significant?

In 33 men, 25 to 40 years old, all with 1 cholesterol measurement exceeding 5.0 mmol/litre, but with no other coronary risk factor, and none of them on a diet or on relevant medication, total serum cholesterol was estimated 12 times in a 4-week period. The mean intraindividual variation coefficient was 5.7%, range from 2.9 to 9.8%. True mean value for the individual based on 1 or 3 estimations and with 90% confidence was assessed.


Accession: 002416157



Related references

Hendriksen, I.J.; Bezemer, P.D.; Boerma, G.J.; Zuiderveld, U., 1992: Variation in serum cholesterol level in the same person: what is the true value and when is it called a significant change?. The blood cholesterol level is not constant over time. Changing values may be found when rechecking high values, especially in patients on a diet or receiving medication. Repeated measurements are necessary. It will then be possible to estimate th...

Schlegel, R.M.ttin, D., 1975: Studies on the intraindividual and interindividual variation of chromosome pairing in diploid and tetraploid rye populations. I. Intraindividual variation. Biologisches Zentralblatt: 94 (5) 539-555

García Díaz, J.Dios.; Hernández Rey, Jé.Miguel.; Gaspar Blázquez, Mía.Jesús.; López de Guzmán, A., 2011: Frequency and intraindividual variation of very low HDL cholesterol. Medicina Clinica 136(11): 504-505

Kobayashi, K.; Sakuratani, Y.; Abe, T.; Nishikawa, S.; Yamada, J.; Hirose, A.; Kamata, E.; Hayashi, M., 2010: Relation between statistics and treatment-related changes obtained from toxicity studies in rats: if detected a significant difference in low or middle dose for quantitative values, this change is considered as incidental change?. The purpose of a toxicity test is to determine the no-observed-effect level (NOEL) of test substance through biological and pharmacological techniques. If the low dose not does show statistically significant and biologically relevant changes in th...

Sartor L.; Horwitz O.; Snyder R.L.; Johnson W.T.M., 1990: The effect of heparin on cholesterol metabolism in the woodchuck change in serum cholesterol sc as a function of initial serum cholesterol isc. FASEB Journal 4(4): A925

Käser, R.; Bruckmaier, R.M.; Thomas, S.; Sieme, H.; Wedekind, C.; Burger, D., 2016: High interindividual and intraindividual variation of oxytocin secretion in estrous mares exposed to stallions, but no significant link to mate preferences. NlmCategory="UNASSIGNED">Oxytocin is a hormone that may not only influence reproductive mechanisms in mammals but also their social behavior, including pair bonding. We therefore tested if the concentrations of oxytocin and other horm...

Leonhardt, W.; Hanefeld, M., 1981: Intraindividual variations of cholesterol and triglyceride concentrations in human serum. Intraindividual variations of cholesterol and triglyceride concentrations were measured at intervals of 1 and 2 days, 1, 2, 3 and 4 weeks, 0.5, 1, 3.5 and 6 years. The observations included normal and high lipid values. Conditions of blood samplin...

Letellier G., 1985: Intraindividual variation of 18 biochemical parameters in the serum over a 10 year period. Annales de Biochimie Clinique du Quebec 24(2): 83

Ortola J.; Fuentes Arderiu X., 1991: Intraindividual and interindividual biological variation of the serum concentration of phospholipids. Clinical Chemistry 37(4): 583

Kiener, S.; Weinbacher, M.; Martina, B.; Keller, U., 1994: Low intraindividual variations of fasting serum triglyceride and total cholesterol in unselected outpatients with mixed hyperlipidemia. Journal of General Internal Medicine 9(4 SUPPL 2): 88