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Intraindividual variation in serum cholesterol. What is the true value and when can a change be considered significant?

Nederlands Tijdschrift voor Geneeskunde 136(31): 1507-1511

Intraindividual variation in serum cholesterol. What is the true value and when can a change be considered significant?

In 33 men, 25 to 40 years old, all with 1 cholesterol measurement exceeding 5.0 mmol/litre, but with no other coronary risk factor, and none of them on a diet or on relevant medication, total serum cholesterol was estimated 12 times in a 4-week period. The mean intraindividual variation coefficient was 5.7%, range from 2.9 to 9.8%. True mean value for the individual based on 1 or 3 estimations and with 90% confidence was assessed.

Accession: 002416157

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