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Intralesional treatment of cutaneous leishmaniasis with sodium stibogluconate antimony

, : Intralesional treatment of cutaneous leishmaniasis with sodium stibogluconate antimony. International Journal of Dermatology 32(8): 610-612

Cutaneous leishmaniasis represents a difficult disease to manage in endemic areas. Systemic treatment is hampered by both expense and compliance. Side effects may play a major role in this aspect as well. The effectiveness of intralesional treatment of leishmaniasis was investigated. Seven hundred and ten patients were treated with injections of sodium stibogluconate intralesionally. The clinical diagnosis was confirmed by demonstrating the parasite in the smears obtained from the lesion. Fine insulin needle was used to infiltrate the lesion with sodium stibogluconate (0.5 to 1.0 mL). Generally eight injections were sufficient, but some of the complicated lesions needed up to 24 injections. Sixty-two percent of patients were men. The majority of the study population (64%) were children below 15 years of age. The results showed that 72% of lesions healed completely, 23.9% showed some improvement, while 4.1% showed some deterioration. Lesions of the lips, cheeks, chin, and neck healed faster than lesions in other parts of the body. Side effects were mild and limited to pain at the site of the injection and hyperpigmentation in those who were treated by folk medicine. Intralesional treatment is as effective as the standard systemic antimonials. It offers a less expensive alternative and a low side effects profile. Our findings confirmed the findings of earlier workers. It is recommended for treatment of cutaneous leishmaniasis in endemic areas.

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Accession: 002416159

PMID: 8407083

DOI: 10.1111/j.1365-4362.1993.tb05044.x

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Soyka, M.; Kranzler, H.R.; van den Brink, W.; Krystal, J.; Möller, H-Jürgen.; Kasper, S.; Kranzler, H.R.; Berglund, M.; Soyka, M.; Möller, H-Jürgen.; Belfort, E.; Choi, I-Geun.; Frey, R.; Gastpar, M.; Gorelick, D.A.; Heinze, G.M.; Hesselbrock, V.; Kosten, T.; Lehert, P.; Lejoyeux, M.; Ling, W.; Mendoza, C.; Musalek, M.; Saito, T.; Srisurapanont, M.; Ujike, H.; Wittchen, U., 2011: The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence. To develop evidence-based practice guidelines for the pharmacological treatment of opioid abuse and dependence. An international task force of the World Federation of Societies of Biological Psychiatry (WFSBP) developed these practice guidelines a...

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Brehm, G., 1974: Immunglobulin E levels in certain dermatoses. Archiv für Dermatologische Forschung 248(4): 329-337

Rogozhin, V.V.; Verkhoturov, V.V., 1999: Mechanism of combined oxidation of ascorbic acid and hydroquinone in the presence of horseradish peroxidase. A steady-state kinetics of peroxidase cooxidation of ascorbic acid and hydroquinone catalyzed by horseradish peroxidase was studied. Ascorbic acid and hydroquinone were shown to be oxidized successively, and hydroquinone promoted the oxidation of...

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Birgens, H.S., 1994: The monocytic receptor for lactoferrin and its involvement in lactoferrin-mediated iron transport. Several studies suggest biological functions of the iron-binding neutrophilic glycoprotein lactoferrin that imply an initial interaction with cells from the monocyte/macrophage family. Among these, an important role of lactoferrin as responsible f...

Fishbein, E.; Alcocer-Varela, J.; Alarcón-Segovia, D., 1983: Cellular bases of the production of and response to interleukin-2 in man: role of autologous rosette-forming T-cell subsets defined with monoclonal antibodies. In this paper we present experiments that indicate that, in man, most T-cell subpopulations produce interleukin-2 (IL-2), but that the main cell subpopulation which produces it, both upon activation with phytohaemagglutinin or in autologous mixed...

Pokarzhevskii Andrei; Eitminaviciute Irena, 2005: Dmitry Krivolutsky 04.10.1939-30.10.2004; obituary. Lietuvos Mokslu Akademija, Ekologija 2005(1): 70

F. Himmerkus, P. Zachariadis, T. Reischmann, D. Kostopoulos, 2012: The basement of the Mount Athos peninsula, northern Greece insights from geochemistry and zircon ages. The Mount Athos Peninsula is situated in the south-easternmost part of the Chalkidiki Peninsula in northern Greece. It belongs to the Serbo-Macedonian Massif (SMM), a large basement massif within the Internal Hellenides. The south-eastern part of...

Townsend, Charles W., 1929: Breeding of the yellow-crowned night heron at Ipswich. Bull Essex County Ornithol Club Massachusetts 11: 27-30