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Intralesional treatment of cutaneous leishmaniasis with sodium stibogluconate antimony


, : Intralesional treatment of cutaneous leishmaniasis with sodium stibogluconate antimony. International Journal of Dermatology 32(8): 610-612

Cutaneous leishmaniasis represents a difficult disease to manage in endemic areas. Systemic treatment is hampered by both expense and compliance. Side effects may play a major role in this aspect as well. The effectiveness of intralesional treatment of leishmaniasis was investigated. Seven hundred and ten patients were treated with injections of sodium stibogluconate intralesionally. The clinical diagnosis was confirmed by demonstrating the parasite in the smears obtained from the lesion. Fine insulin needle was used to infiltrate the lesion with sodium stibogluconate (0.5 to 1.0 mL). Generally eight injections were sufficient, but some of the complicated lesions needed up to 24 injections. Sixty-two percent of patients were men. The majority of the study population (64%) were children below 15 years of age. The results showed that 72% of lesions healed completely, 23.9% showed some improvement, while 4.1% showed some deterioration. Lesions of the lips, cheeks, chin, and neck healed faster than lesions in other parts of the body. Side effects were mild and limited to pain at the site of the injection and hyperpigmentation in those who were treated by folk medicine. Intralesional treatment is as effective as the standard systemic antimonials. It offers a less expensive alternative and a low side effects profile. Our findings confirmed the findings of earlier workers. It is recommended for treatment of cutaneous leishmaniasis in endemic areas.

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Accession: 002416159

PMID: 8407083

DOI: 10.1111/j.1365-4362.1993.tb05044.x

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Middel, P.; Reich, K.; Polzien, F.; Blaschke, V.; Hemmerlein, B.; Herms, J.; Korabiowska, M.; Radzun, H.J., 2001: Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease. Background: The mechanisms involved in the initiation and maintenance of Crohn's disease are poorly understood. Previous studies have demonstrated an increased number of infiltrating CD4+ T cells within the inflammatory affected bowel wall in...

Larson, T.R.; Robertson, D.W.; Corica, A.; Bostwick, D.G., 2000: In vivo interstitial temperature mapping of the human prostate during cryosurgery with correlation to histopathologic outcomes. Objectives: To determine the critical temperatures below which human prostatic tissue can be cryoablated in situ and the comparative cryoablative efficacy of single versus double-freeze cryosurgery. Methods: Six patients with prostate cancer previ...

Artem' eva, T.; Terent' ev, A.; Orlov, O., 1989: Successional changes of microarthropods on introducing organic fertilizers into soil contaminated by oil. Data are presented on the effects of microarthropod populations on the decomposition of manure and straw in oil-contaminated soil.

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Del Giudice, M., 2011: Sex differences in romantic attachment: a meta-analysis. This article presents the first meta-analysis of sex differences in the avoidance and anxiety dimensions of adult romantic attachment, based on 113 samples (N = 66,132) from 100 studies employing two-dimensional romantic attachment questionnaires...

Takahashi N.; Inoue T.; Fujino T.; Ito M.; Saikawa T.; Arita M., 1991: Characteristics of ventricular tachycardia induced by cesium chloride in rabbits in vivo. Japanese Circulation Journal 55(SUPPL A): 197

Couch, J.A.; Winstead, J.T.; Goodman, L.R., 1977: Kepone-induced scoliosis and its histological consequences in fish. Scoliosis in fish is caused by several diverse agents that possibly act on the central nervous system, neuromuscular junctions, or ionic metabolism. The organochlorine pesticide Kepone induces scoliosis in the sheepshead minnow. Some effects assoc...

Cariou, D.; Aerts, J.; Pasquier, P., 1993: Osteoarticular pain in AIDS. Original course. Presse Medicale 22(18): 877-877

Koneva, O.V.; Khaibullina, Z.G., 1994: Effect of synthetic antioxidants on hematological characteristics of rats after intoxication. Uspekhi Fiziologicheskikh Nauk 25(3): 49

Allen, W.M.; Drake, C.F., 1986: Controlled release of mineral nutrients and other pharmaceuticals for sheep and cattle. Controlled-release glass (soluble glass) containing copper was unsuitable for subcutaneous implantation into cattle, but it could be administered orally as a 75 g bolus, providing a continuous supply of Cu for up to a year. Cobalt could also be in...