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Intramuscular injection as a provoking factor for paralysis in acute poliomyelitis. A case control study


, : Intramuscular injection as a provoking factor for paralysis in acute poliomyelitis. A case control study. Indian Pediatrics 30(3): 335-340

Provocative injections cause paralysis 7-20+ days after, with changes in pattern and severity. In this study children who developed poliomyelitis had up to 3 times the chance of having received intramuscular injections than matched children with acute respiratory infections or fever. However, only 35% of the 172 children with paralysis fitted this time scale and correlation of paralysis with injection was slight.


Accession: 002416173

PMID: 8365783

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Related references

Thiodet, J.; Massonnat, J.; Fourrier, A.; Courtine, J.C., 1960: Apropos of provoking factors in acute poliomyelitis: early lumbar puncture and poliomyelitic paralysis. Algerie Medicale 64: 623-633

Nathanson, N.; Bodian, D., 1962: Experimental poliomyelitis following intramuscular virus injection. III. The effect of passive antibody on paralysis and viremia. Bulletin of the Johns Hopkins Hospital 111: 198-220

Anonymous, 1932: Poliomyelitis I Production of antiviral serums by inoculation of goats and sheep with the virus of poliomyelitis II Comparison of intramuscular injection with combined intraspinal and intravenous injection of convalescent serum in the treatment for experimental poliomyelitis in monkeys

Levi, W.M.; Ferrara, B.E., 1958: The preferred site of intramuscular injection; report of a case of peripheral nerve paralysis following intramuscular therapy. Journal of the South Carolina Medical Association 54(2): 44-48

Mathur, G.P.; Gahlaut, I.V.; Mathur, S.; Upadhyay, G.C.; Gupta, V.K., 1994: Intramuscular injection as a provocative factor in paralytic poliomyelitis. Indian Pediatrics 31(5): 529-531

Mayer, M.; Romain, O., 2001: Sciatic paralysis after a buttock intramuscular injection in children: an ongoing risk factor. Intramuscular injections are regularly recommended for the administration of certain drugs in children. This article underlines the fact that buttock intramuscular injection risks injury to the sciatic nerve, which may lead to lower limb palsy, mo...

Gogstad, A.C., 1951: Poliomyelitis with paralysis after vaccination and intramuscular injections. Nordisk Medicin 46(27): 1042-1044

Bury, J.S., 1902: A Case Of Complete And Temporary Paralysis Of The Limbs In A Child, Probably A Case Of Recovery From The Initial Stage Of Acute Anterior Poliomyelitis. British Medical Journal 1(2160): 1258-1259

Bergamini, F.; Giannelli, F., 1961: Contribution to the study of the etiology of some acute diseases of the central nervous system (poliomyelitis, facial paralysis, encephalitis, aseptic meningitis). Diagnostic observations in 175 patients vaccinated and not vaccinated against poliomyelitis. Bollettino Dell'istituto Sieroterapico Milanese 40: 236-245

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