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Intravascular metabolism of different fatty acids during lipid infusion in man

, : Intravascular metabolism of different fatty acids during lipid infusion in man. Clinical Nutrition (Edinburgh) 12(6): 329-336

The differential intravascular metabolism of individual fatty acids contained in triacylglycerol-rich particles was studied by infusing 6 normal subjects for 5 h with a conventional soy-based emulsion and an experimental olive oil-based emulsion. Both emulsions contained similar amounts of palmitate (11%) and stearate (3-4%) but the former was quite rich in linoleate (54%) and alpha-linolenate (7%), while the latter was rich in oleate (69%). During hydrolysis of circulating triacylglycerols by endothelial lipases, the associated rise of non-esterified fatty acids (FFA) in plasma represents the balance between fatty acid release and tissue uptake. Plasma levels of triacylglycerols and FFA increased about 3 fold and total body fat oxidation was raised to similar values with both emulsions. Fatty acid pattern quickly changed in plasma triacylglycerols to resemble the composition of emulsion particles, with an exception for palmitate which increased markedly more, suggesting a high level of hepatic re-esterification and reappearance in nascent very low density lipoprotein triglycerides (VLDL-TG) secreted into the circulation. In plasma FFA, stearate and palmitate increased more and alpha-linolenate much less than expected from their content in the emulsion, indicating probably low tissue uptake for the former ones but avid removal for the latter.

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Accession: 002416290

PMID: 16843334

DOI: 10.1016/0261-5614(93)90028-3

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Thompson, J.S., 1985: Colistin-oxolinic acid blood agar: a selective medium for the isolation of Gardnerella vaginalis. Colistin-oxolinic acid medium is proposed as a selective isolation medium for Gardnerella vaginalis. The medium is effective in inhibiting staphylococci and gram-negative bacteria while allowing growth of G. vaginalis.

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BONGIOVANNI.A.M.; EBERLEIN.W.R.; SMITH.J.D.; McPADDEN.A.J., 1959: The urinary excretion of three C-21 methyl corticosteroids in the adrenogenital syndrome. Three of the more abundant C-21 methyl corticosteroids were measured in the urine of 11 patients (aged 2 weeks to 23 years) with the adrenogenital syndrome, and compared with the excretion in normal controls and 4 cases of virilizing adrenal adeno...

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