+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Invasive amoebiasis is associated with the development of anti-neutrophil cytoplasmic antibody

, : Invasive amoebiasis is associated with the development of anti-neutrophil cytoplasmic antibody. Clinical & Experimental Immunology 97(1): 48-51

Features of tissue damage in invasive amoebiasis, in particular polymorphonuclear neutrophil (PMN) degranulation and vasculitis, bear resemblance to that seen in Wegener's granulomatosis, the latter being associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). We therefore tested sera from patients with confirmed amoebic liver abscess (ALA) for the presence of ANCA by means of an indirect fluorescent antibody test using pure neutrophils as substrate. ANCA was detected in 97.4% of amoebic sera; the pattern of staining was cytoplasmic, homogeneous, without central accentuation (C-ANCA). A proteinase 3 (PR3) ELISA demonstrated PR3 specificity in 75% of C-ANCA-positive ALA sera. Possible explanations are (i) a cross-reacting antibody to a component of Entamoeba histolytica, or (ii) an antibody to PMN components released, and possibly modified, by the action of E. histolytica on PMN. It is possible that this antibody contributes to the pathogenesis of invasive amoebiasis.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 002416586

PMID: 8033420

DOI: 10.1111/j.1365-2249.1994.tb06578.x

Download PDF Full Text: Invasive amoebiasis is associated with the development of anti-neutrophil cytoplasmic antibody

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Hodges, M.R.; Forster, H.; Pan, L.; Bastasic, J.; Davis, S.; Opansky, C.; Martino, P., 2004: Effects of Simultaneous Focal Acidification at Multiple Medullary Sites in Awake Goats. The purpose of this study was to determine the acute effects of focal acidosis (FA) at multiple medullary chemoreceptor sites in awake goats. Microtubules were chronically implanted into the caudal (CMR, n=2) and/or rostral medullary raphe (RMR, n...

Soriano, G.; Guarner, C., 1997: Primary prophylaxis of spontaneous bacterial peritonitis. Gastroenterologia Y Hepatologia 20(6): 312-314

Myers, Charles W., 1963: Ontogenetic color variation of the snake Virginia valeriae. Ventral coloration of V. v. elegans changes from grayish-white to yellow-green in the life of an individual; there are probably changes in the intensity of dorsal pigmentation also. Most species of snakes probably exhibit ontogenetic variation in...

Loor, F.; Kelus, A.S., 1978: Allelic exclusion in the B lineage cells of the rabbit. Allelic exclusion of the kappa polypeptide chain allotypes b4 and b5 of the rabbit exists for the immunoglobulins of almost all plasma cells and of most mature small B cells. However, both these alleles are expressed simultaneously in rare plasma...

FUHS, G.W., 1958: Composition, behavior and importance of nucleus-like structures in Oscillatoria amoena (Kutz.) Gomont. Archiv für Mikrobiologie 28(3): 270-302

Waldmann, O.; Kobe, K.; Pape, J., 1934: Aetiology of Hoppegarten Cough. Hoppegarten cough. is a contagious disease of horses affecting the respiratory system, caused by an ultra-visible, filtrable virus. This produces a catarrhal bronchitis and peribronchitis, together, with pulmonary consolidation. No bacteria are pr...

Berroteran, J. L., 1995: Establishment and yield of Andropogon gayanus Kunth and maize (Zea mays L.) in mixture in the Llanos de Venezuela. In field trials in 1986 on well-drained savanna in the Venezuelan Llanos region, maize cv. PB8 was sown at a rate of 63 000 plants/ha in rows 90 cm apart with A. gayanus cv. CIAT 621 sown between rows and given 28 kg N, 25 kg P and 24 kg K/ha. Gro...

Kobayashi J.; Wong A.; Hwang P.; Murphy E.G.; Hoffman H., 1985: Surgery for intractable seizures in infants and children. Canadian Journal of Neurological Sciences 12(2): 178

Vivancos, J.; Vila, M.; Serra, A.; Loscos, J.; Anguita, A., 2002: Failure of G-CSF therapy in neutropenia associated with Sjogren's syndrome. Rheumatology (Oxford) 41(4): 471-473

Barlow, M., 1990: "Persistent vegetative state". Nursing Rsa 5(5): 45-45