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Investigation of selenium sources associated with chronic selenosis in horses of western Iowa


, : Investigation of selenium sources associated with chronic selenosis in horses of western Iowa. Journal of Veterinary Diagnostic Investigation 5(1): 128-131

Toxic levels (up to 58 ppm) of selenium in alfalfa (Medicago sativa) produced on soils with apparently normal selenium (Se) content (0.5-1.25 ppm) resulted in chronic selenosis when fed to horses.

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Accession: 002416873

PMID: 8466974

DOI: 10.1177/104063879300500133

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Related references

Baker, D.; James, L.; Panter, K.; Mayland, H.; Pfister, J., 1987: Selenosis in developing pigs fed selenium from different sources. Journal of animal science5(1): 351

Smith, M.I.; Lillie, R.D.; Stohlman, E.F.; Westfall, B.B., 1940: Studies in chronic selenosis. 1. The chronic toxicity of naturally occurring food selenium. Chronic Se poisoning in rabbits, rats and cats for periods up to 1 year was studied. The results showed wide variations of susceptibility in animals and in none of the species studied were the abnormalities suggestive of " alkali disease &quo...

Smith, M.I.; Lillie, R.D.; Stohlman, E.F.; Westfall, B.B., 1940: Studies in chronic selenosis. 2. Gastric acidity in chronic selenium poisoning. The gastric secretion of rats and cats suffering from chronic Se poisoning induced by feeding either inorganic Se or naturally seleniferous foods was stimulated by oral administration of 7 per cent. alcohol solution or by subcutanebusly injected h...

Smith, M.I.; Lillie, R.D., 1940: Studies in Chronic Selenosis. Part I. The Chronic Toxicity of Naturally Occurring Food Selenium. It is considered that continued excretion of selenium in the urine up to a level of 500 micro g.% need not necessarily be associated with pronounced symptoms of selenium poisoning in animals or man. Food selenium is less toxic than sodium selenite...

Smith, M.I.; Lillie, R.D.; Stohlman, E.F.; Westfall, B.B., 1940: Studies in chronic selenosis. 3. Liver function and bile pigments in experimental chronic selenium poisoning. Rabbits and cats suffering from chronic Se poisoning did not show bilirubinaemia and urinary urobilinogen was not raised above the level in control animals. Rose bengal and bilirubin, when intravenously injected, were retained in circulation in ab...

Smith, M.I.; Lillie, R.D.; Stohlman, E.F.; Westfall, B.B., 1940: Studies in chronic selenosis. 4. Selenium in the hair as an index of the extent of its deposition in the tissues in chronic poisoning. A nephelometric method for the estimation of Se in blood, urine and tissues is described. The error of the method was +or- 10 per cent. The Se contents of urine, blood, liver and hair are given for rabbits and cats, chronically poisoned with Se, a...

Smith, M.I.; Westfall, B.B.; Stohlman, E.F., 1940: Studies in Chronic Selenosis. Part III. Liver Function and Bile Pigments in Experimental Chronic Selenium Poisoning. III. Experiments on rabbits and cats showed that chronic poisoning by voluntary ingestion of foods containing selenium is associated with appreciable chronic interstitial hepatitis. The rose-bengal test seemed more specific in discerning liver dys...

Westfall, B.B.; Smith, M.I., 1940: Studies in Chronic Selenosis. Part IV. Selenium in the Hair as an Index of the Extent of its Deposition in the Tissues in Chronic Poisoning. IV. Data are presented from simultaneous analyses of hair, liver, kidneys, blood, and urine of cats and rabbits fed on selenium-bearing cereals for considerable periods. The method for selenium determination in biological materials is described in...

McLaughlin, J.G.; Cullen, J., 1986: Clinical cases of chronic selenosis in horses. The rapid onset of clinical signs of severe chronic selenosis (hair loss, cracked hooves, depression, and lameness) was observed in a four-year-old mare grazing seleniferous pastures in County Meath. The onset was more insidious and the clinical s...

Witte, S.T.; Will, L.A.; Olsen, C.R.; Kinker, J.A.; Miller-Graber, P., 1993: Chronic selenosis in horses fed locally produced alfalfa hay. Chronic selenosis (alkali disease) was diagnosed in horses of western Iowa, a region associated with marginal to adequate soil selenium. Two locally produced alfalfa hays (Medicago sativa L) were identified as the primary source. Difficulty in sel...