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Investigation of the effect of the malarial drug dabekhin on the haemostatic system and anticoagulant effect of heparin


Farmakologiya i Toksikologiya 53(1): 59-62
Investigation of the effect of the malarial drug dabekhin on the haemostatic system and anticoagulant effect of heparin
The effect of dabekhin (an antimalarial synthesized in Russia in 1968) on blood coagulation was investigated in a series of experiments. In vitro, dabequine delayed blood coagulation time, plasma recalcification time and thrombin time, and showed a dose-related neutralizing effect on heparin; association of dabequine and heparin reduced the specific activity of the anticoagulant.


Accession: 002416906



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