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Neuropathology of chronic wasting disease of mule deer (Odocoileus hemionus) and elk (Cervus elaphus nelsoni)



Neuropathology of chronic wasting disease of mule deer (Odocoileus hemionus) and elk (Cervus elaphus nelsoni)



Veterinary Pathology 30(1): 36-45



The pathology of the central nervous system of 9 mule deer and 6 elk with chronic wasting disease, a spongiform encephalopathy of mule deer and elk, was studied by light microscopy. Lesions were similar in both species and were characterized by spongiform transformation of gray matter, intracytoplasmic vacuolation of neurons, neuronal degeneration and loss, astrocytic hypertrophy and hyperplasia, occurrence of amyloid plaques, and absence of inflammatory response.

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Accession: 002440816

Download citation: RISBibTeXText

PMID: 8442326

DOI: 10.1177/030098589303000105


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