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Prolactinomas and functional hyperprolactinaemia


, : Prolactinomas and functional hyperprolactinaemia. Biologie de la lactation: 143-166

Research into the development of prolactinoma in humans is reviewed, under the 3 broad headings: prolactinoma, functional hyperprolactinaemia and physiopathological data.


Accession: 002468956

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Related references

Mann, W.Alexander., 2011: Treatment for prolactinomas and hyperprolactinaemia: a lifetime approach. Prolactinomas are the most common hormone-secreting pituitary tumours and are amenable to medical therapy with dopamine agonists. Indication for treatment will most commonly result from hypogonadism, infertility or symptoms related to tumour size....

Schwetz, V.; Librizzi, R.; Trummer, C.; Theiler, G.; Stiegler, C.; Pieber, T.R.; Obermayer-Pietsch, B.; Pilz, S., 2016: Treatment of hyperprolactinaemia reduces total cholesterol and LDL in patients with prolactinomas. NlmCategory="UNASSIGNED">Previous studies suggest that hyperprolactinaemia might have adverse effects on lipid and glucose metabolism. We therefore aimed to evaluate whether dopamine agonist treatment with cabergoline has significant...

Batrinos, M.L.; Panitsa-Faflia, C.; Tsiganou, E.; Pitoulis, G.; Liapi, C., 1994: Contribution to the problem of hyperprolactinaemia: experience with 4,199 prolactin assays and 117 prolactinomas. To help define the normal and pathological serum prolactin concentration ranges in adult females. Serum prolactin was assayed in a mixed population of 4,199 women divided into five groups: (A) 753 with normal menses consulting for infertility (con...

Scanlon, M.F.; Peters, J.R.; Salvador, J.; Richards, S.H.; John, R.; Howell, S.; Williams, E.D.; Thomas, J.P.; Hall, R., 1986: The preoperative and postoperative investigation of TSH and prolactin release in the management of patients with hyperprolactinaemia due to prolactinomas and nonfunctional pituitary tumours: relationship to adenoma size at surgery. We report here our results of the pre- and post-operative assessment of prolactin and TSH status in 41 hyperprolactinaemic patients who underwent pituitary surgery over a 5 year period. Preoperatively in patients with prolactinomas (n = 33) the TS...

Su, H-wen.; Chen, C-min.; Chou, S-yuan.; Liang, S-jung.; Hsu, C-sen.; Hsu, M-i., 2011: Polycystic ovary syndrome or hyperprolactinaemia: a study of mild hyperprolactinaemia. Polycystic ovary syndrome (PCOS) and hyperprolactinaemia are both common causes of secondary amenorrhoea in reproductive women. The relationship between PCOS and hyperprolactinaemia has been reported with controversial results. To evaluate the cli...

Labad, J., 2016: Spanish consensus on the risks and detection of antipsychotic drug-related hyperprolactinaemia: Is there convergence with other clinical guidelines for the management of hyperprolactinaemia?. Revista de Psiquiatria Y Salud Mental 9(3): 174-175

Pavelka, R.; Schmid, R.; Schneider, W.H.; Spona, J., 1979: Hormonal and functional parameters in hyperprolactinaemia. 58 women with raised serum prolactin levels and normal hypophyseal X-ray parameters were subdivided into three groups according to the serum prolactin level (16 to 40, 41 to 80, greater than 80 ng/ml). In addition to the determination of LH, FSH,...

Azad, N.; Nayyar, R.; Tentler, J.; Cernius, M.; Emanuele, N.V.; Kirsteins, L.; Lawrence, A.M., 1989: Anatomical and functional effects of estrogen-induced prolactinomas on the rat hypothalamus. Although estrogen-induced prolactinomas have been widely studied, little attention has been accorded to local pressure effects of the tumor on the hypothalamus and portal vasculature. To portray the magnitude of this phenomenon, four groups of 12-...

Pereira M.C.; Sobrinho L.G.; Afonso A.M.; Nunes M.C.P.; Soczka L.; Santos M.A.; Mauricio J.C.; Sousa M.F.F., 1985: Evidence that prolactinomas may represent late stages of functional hyperplasia of the lactotrophs. Journal of Endocrinological Investigation 8(SUPPL 3): 204

Jaquet, P.; Ouafik, L.; Saveanu, A.; Gunz, G.; Fina, F.; Dufour, H.; Culler, M.D.; Moreau, J.P.; Enjalbert, A., 1999: Quantitative and functional expression of somatostatin receptor subtypes in human prolactinomas. Recently, it was demonstrated that somatostatin analogs preferential for the SSTR5 subtype suppress PRL release from prolactinoma cell cultures by 30-40%. These data supported the idea of somatostatin receptor subtype-specific control of PRL secre...