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The use of ATP bioluminescence in UHT sterility testing

, : The use of ATP bioluminescence in UHT sterility testing. Milk Industry London 96(7, Technical and Processing Supplement): 12-13

An account is given of the use of the Lumac ATP bioluminescence technology in UHT sterility testing. In order to validate the test, Gram-negative and Gram-positive cultures were inoculated into cartons of UHT milk through a self-sealing rubber patch at a level of 1-10 cells/carton. Cartons were incubated at 30 degrees C and tested daily for 3 days by both the Lumac method and by plating. After 48 h, 97% of all cartons tested showed growth and all such cartons were detected by the Lumac method.

Accession: 002530032

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Bussey, D.M.; Tsuji, K., 1986: Bioluminescence for USP sterility testing of pharmaceutical suspension products. Bioluminescence measurement significantly improved the accuracy, sensitivity, precision, and reliability of the current visual endpoint determination for the USP sterility test and eliminated the day 7 transfer/dilution step required for testing s...

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