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The use of genetic analysis in the study of the biology of Candida albicans

, : The use of genetic analysis in the study of the biology of Candida albicans. The genetics of Candida: 187-196

Genetic approaches to the study of C. albicans biology, including ploidy, life cycle, role of extracellular proteinase in virulence, drug resistance, yeast-to-hyphal transition, effects of various kinds of mutations on virulence, other aspects of Candida biology and future directions are discussed.

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Bennett, D.E.; McCreary, C.E.; Coleman, D.C., 1998: Genetic characterization of a phospholipase C gene from Candida albicans: presence of homologous sequences in Candida species other than Candida albicans. Phospholipase C (PLC) enzymes are essential in regulating several important cellular functions in eukaryotes, including yeasts. In this study, PCR was used to identify a gene encoding PLC activity in Candida albicans, using oligonucleotide primers...

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