+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The use of isophane insulin for the control of diabetes mellitus in dogs

, : The use of isophane insulin for the control of diabetes mellitus in dogs. Acta Veterinaria Scandinavica 33(3): 219-227

For this study 54 dogs with diabetes mellitus verified by anamnesis, clinical examinations and laboratory analyses were selected in 13 Danish and Swedish small animal clinics. After instruction the owners gave isophane insulin ("Insulin Protaphan Human") injections to the dogs morning and evening followed by a commercial or homemade meal rich in fibers. The veterinarians examined the treated dogs 5 times or more in the 90-day treatment period, preferably in the morning before injection and meal. In all 54 dogs the clinical symptoms disappeared a few days after isophane insulin injections, and 54% of the dogs were clinically healthy within 8 days. Within a month 96% of the dogs were normalized after therapy. Simultaneously the blood glucose levels were normalized in 64% of the dogs within 14 days and further 21% within 30 days. The urine glucose levels were normalized in 64% of the dogs within 14 days and for further 19% within 30 days. At the end of the study 48 out of the 54 diabetic dogs were clinically healthy, alert and free from symptoms of diabetes. The average dose of isophane insulin was for greater dogs 0.44 units per kg bw twice a day, for small dogs 0.79. Six dogs had been destroyed in the trial period for various reasons. One owner had injection troubles. Another owner was hospitalized and had to get rid of the dog. One dog developed advanced breast cancer, 1 went fierce and 2 developed cataracts. Four dogs had by 1 or 2 occasions shown hypoglycemic symptoms, which quickly disappeared after appropriate adjustments of insulin dosing, feeding schedule and exercise program. It can be concluded that isophane insulin is a highly suitable insulin preparation for a 2 injection per day treatment of diabetic dogs.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 002530393

PMID: 1442369

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

James A.E.Jr, 1984: The detection of acute splenic and renal infarcts on contrast enhanced magnetic resonance imaging. Investigative Radiology: S25

Stokes G.V., 1977: Separation of vaccinia virus surface proteins. Abstracts Of The Annual Meeting Of The American Society For Microbiology: 0

Seino, Hiroaki; Hirata, Akihiko; Yamaguchi, Hirosi; Yamazaki, Toshio; Kikuchi, Hiroaki; Abe, Ryuzo, 1996: A case of slowly progressive IDDM with anti-GAD antibody detectable even after a 20 year duration of diabetes. A 69-year old male was first admitted to our hospital at age 49 years, in May 1976, complaining of positive urinary glucose. The first examination in our hospital demonstrated a fasting plasma glucose level of 139 mg/dl while urinary ketones were...

Kerr, EA.; Yu, N-T.; Bartnicki, DE.; Mizukami, H., 1985: Resonance Raman studies of CO and O2 binding to elephant myoglobin (distal his (E7) Gln). CO and O2 were employed as resonance Raman-visible ligands for probing the nature of the heme-binding site in elephant myoglobin (Mb), which has glutamine in the distal position (E7) instead of the usual histidine. The distal histidine (E7) residu...

Fleit H.B.; Rabinovitch M., 1981: Production of interferon by in vitro derived bone marrow macrophages. Interferon [IF] production by essentially pure populations of bone-marrow-derived macrophages [murine] was examined after induction with lipopolysaccharide (LPS) [Salmonella abortus equi, Escherichia coli], polyinosinic:polycytidylic acid (poly (I...

Spahni, P., 1995: The international wine trade. During the last two decades there have been significant changes in the international wine trade, including the effect of supermarkets retailing to consumers, the technological revolution engineered by New World producers, and the changes taking pl...

Makarova I. R.; Dojnikova E. (Doynikova Ye), 1995: Miospores and conodonts in Carboniferous-Permian deposits of South Urals. Pages 93 1995

Burtt B.L., 1985: A new species of helichrysum compositae from malawi. Helichrysum polioides is described from montane grassland on Mt Mulanje, Malawi. It is a dwarf shrub with spathulate leaves and tight woolly inflorescences of small homogamous capitula.

Morin, Jf, 1979: Disinfection of sugarbeet seeds. A. From seeds to young plants: the first indispensable protection. Cultivar (122) 29

Yoshii, Chiharu; Matsuyama, Tsuneo; Takazawa, Akiko; Ito, Toshiro; Yatera, Kazuhiro; Hayashi, Toshinari; Imanaga, Tomotoshi; Kido, Masamitsu, 2002: Welder's pneumoconiosis: Diagnostic usefulness of high-resolution computed tomography and ferritin determinations in bronchoalveolar lavage fluid. Objective: We assessed the usefulness of high-resolution computed tomography (HRCT) and ferritin determinations in bronchoalveolar lavage (BAL) fluid for diagnosis of welder's pneumoconiosis. Patients and Methods: We investigated 11 patients...