EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The uterine relaxant effect of Aloe chabaudii






Fitoterapia 65(3): 253-259

The uterine relaxant effect of Aloe chabaudii

A crude extract of the leaves of A. chabaudii inhibited the spontaneous contractions of the isolated rat uterus. The inhibitory effect (lid not appear to be due to its content of potassium ions nor due to stimulation of beta-2-receptors since propranolol which blocked isoprenaline-induced relaxation on the uterus had no effect on the aloe-induced inhibitory response. A non-specific membrane depressant effect is also not likely since the aloe extract had no effect on the contractile response to acetylcholine and oxytocin. The possibility of the aloe action on H-2 receptors is discussed as well as its possibility in blocking the phosphodiesterase enzyme and thereby increasing intracellular cyclic AMP. A. chabaudii therefore does not possess abortifacient activity and should not be used for this purpose.


Accession: 002530733



Related references

Aloe chabaudii var. mlanjeana. Aloe 37(4): 91, 2000

Drug preservatives and uterine contractility chloro butanol relaxant ethyl alcohol relaxant phenol relaxant sodium acetate relaxant woman. American Journal of Obstetrics & Gynecology 94(1): 1-5, 1966

Relaxant effect of cyclic amp on the isolated rabbit ileum epinephrine autonomic phentolamine relaxant adenosine relaxant sotalol relaxant. Journal of Pharmacology and Experimental Therapeutics 163(1): 36-42, 1968

Epinephrine derivates and the activity of the human uterus i the inhibiting effect of p hydroxyphenylisopropyl arterenol relaxant cc 25 relaxant upon uterine activity in human pregnancy. American Journal of Obstetrics & Gynecology 92(6): 865-870, 1965

The pharmacology of pancuronium bromide relaxant a new non depolarizing neuro muscular blocking agent cat pavulon relaxant neostigmine relaxant atropine autonomic halothane relaxant thiopentone relaxant. Irish Journal of Medical Science 1(12): 565-568, 1968

Effect of Aloe barbadensis on rat's uterine contractility. Nigerian Journal of Health and Biomedical Sciences 3(2): 120-122, 2004

Relaxant effect of diazepam on uterine muscle. Obstetrics and Gynecology 26(4): 552-556, 1965

Clinical effect of dactil-OB as an uterine relaxant. Sanfujinka No Jissai. Practice of Gynecology and Obstetrics 14(9): 768-771, 1965

The uterine relaxant effect of curcumin in rats; an in vitro study. 2008

Relaxant effect of Levosimendan on human uterine contractility in vitro. American Journal of Obstetrics and Gynecology 203(2): 184.E7-12, 2010