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3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes


, : 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes. Antimicrobial Agents and ChemoTherapy 38(5): 1144-1148

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit the in vitro intraerythrocytic development of Plasmodium falciparum and Babesia divergens, with concentrations inhibiting parasite growth by 50% in the ranges of 10 to 20 and 5 to 10 micro g/ml, respectively.

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Accession: 002549928

PMID: 8067753

DOI: 10.1128/AAC.38.5.1144

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Granerus G.; Wass U., 1984: Urinary excretion of histamine methylhistamine and methylimidazoleacetic acid in mastocytosis comparison of new high liquid chromatography performance methods with other present methods. Agents & Actions 14(3-4): 341-345

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Del Valle Zuris, A.; Hauck, H., 2003: Physiological and metabolic responses of a 64 year-old ex-UDT male to 24 hours continuous swim. Medicine & Science in Sports & Exercise 35(5 Supplement): S205, May

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