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4'-O-Methylstephavanine from Stephania abyssinica

, : 4'-O-Methylstephavanine from Stephania abyssinica. Journal of Natural Products 56(11): 2022-2025

The leaves of S. abyssinica are used as a purgative and emetic, and the roots are used to treat roundworm, menorrhagia and boils. Stephavanine, and a new alkaloid, 4'-O-methylstephavanine, were isolated from the EtOH extract of the roots of S. abyssinica (collected from central Ethiopia). Their structures were determined from spectral data.

Accession: 002549968

PMID: 8289070

DOI: 10.1021/np50101a029

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Related references

Dagne, E.; Gunatilaka, A.A.; Kingston, D.G.; Alemu, M., 1993: 4'-O-methylstephavanine from Stephania abyssinica. Journal of Natural Products 56(11): 2022-2025

Kande, K.M.moudu; Philipov, S.; Dutschweska, H., 1994: Alkaloids of Stephania abyssinica. Fitoterapia 65(1): 90

Chakraborty, A.; Asres, K.; Stipsits, S.; Eibl, U.; Brantner, A.H., 2000: Biological properties of Stephania abyssinica roots. The in vitro antimicrobial and antioxidant properties of Stephania abyssinica root extract and fractions were investigated. The antimicrobial tests were performed by the hole-plate method. The crude MeOH extract and the alkaloids showed a remarkab...

Kupchan, S.M.; Liepa, A.J.; Fujita, T., 1973: New phenolic Hasubanan alkaloids from Stephania abyssinica. Journal of Organic Chemistry 38(1): 151-153

Omole, R.A.; Gathirwa, J.; Akala, H.; Malebo, H.M.; Machocho, A.K.; Hassanali, A.; Ndiege, I.O., 2014: Bisbenzylisoquinoline and hasubanane alkaloids from Stephania abyssinica (Dillon & A. Rich) (Menispermeceae). Two bisbenzylisoquinoline and one hasubanane alkaloids: (-)-pseudocurine (1), (-)-pseudoisocurine (2) and (-)-10-oxoaknadinine (3), were isolated from leaf extract of Stephania abyssinica, a plant used in traditional medicine in South Nyanza regio...

Kupchan, S.M.; Suffness, M.I.; Gordon, E.M., 1970: The isolation and structure elucidation of oxoxylopine, a new oxoaporphine alkaloid from Stephania abyssinica. Journal of Organic Chemistry 35(5): 1682-1684

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Paris, R.; L.M.N.J., 1955: A species of Stephania from French West Africa: Stephania dinklagei Diels (Menispermaceae). Annales Pharmaceutiques Francaises 13(3): 200-204

Kaz Mina L.P.; Rabinovich I.M., 1968: Pharmacognostic study of the smooth leaved stephania d stephania glabra d transcaucasia ussr 1 tetra hydro palmatine alkaloid. Farmatsiya 17(3): 39-45

Lock, J.A., 1962: Cardiotonic substances from Bersama abyssinica fres. sub. species abyssinica. Journal of Pharmacy and Pharmacology 14: 496-502