+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Calcium, iron, zinc, copper and manganese bioavailability from infant formulas and weaning diets assessed in rat pups



Calcium, iron, zinc, copper and manganese bioavailability from infant formulas and weaning diets assessed in rat pups



Nutrition research 14(10): 1535-1548



A suckling rat pup model was used to evaluate the absorption of calcium, iron, zinc, copper, and manganese from various types of infant formulas and weaning foods. Radioisotopes were used to extrinsically label the diets and absorption was measured 6 h after introduction of the diets by gastric needle into fasted pups. Mineral and trace element absorption from regular cow milk formulas, hydrolysate formulas and premature formulas was high (Ca: 72-86%; Fe: 89-96%; Zn: 78-99%; Cu: 75-86%; Mn: 75-85%) and similar to that from human milk. Bioavailability of calcium and trace elements from soy formula and weaning formulas containing cereals or rice was significantly lower, most likely due to the presence of phytate in these products. Knowledge of various factors in infant formulas that affect mineral and trace element absorption negatively may help when making dietary choices and also when designing weaning diets for infants. In addition, such data give suggestions for possible changes in the composition of infant formulas that can lead to improved mineral and trace element bioavailability.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 002573653

Download citation: RISBibTeXText

DOI: 10.1016/s0271-5317(05)80232-5


Related references

Iron, zinc, copper, and manganese in infant formulas. American Journal of Diseases of Children 137(5): 433-437, 1983

Copper, iron, zinc, and manganese in dietary supplements, infant formulas, and ready-to-eat breakfast cereals. American Journal of Clinical Nutrition 67(5 Suppl): 1035s-1040s, 1998

Calcium phosphorus magnesium zinc copper and manganese content of infant formulas produced in the usa. Federation Proceedings: 359, 1986

The effect of casein phosphopeptides on zinc and calcium absorption from high phytate infant diets assessed in rat pups and Caco-2 cells. Pediatric Research 40(4): 547-552, 1996

High- versus low-meat diets: effects on zinc absorption, iron status, and calcium, copper, iron, magnesium, manganese, nitrogen, phosphorus, and zinc balance in postmenopausal women. American journal of clinical nutrition 62(3): 621-632, 1995

Calcium phosphorus magnesium zinc copper manganese sodium potassium and chlorine contents of infant formulas manufactured in the usa. Journal of Food Composition & Analysis 2(2): 132-139, 1989

In vitro interactions between calcium, zinc, copper and iron in milk- and soy-based infant formulas. Food Science & Technology International 6(1): 25-31, 2000

Effect of dephytinization on bioavailability of iron, calcium and zinc from infant cereals assessed in the Caco-2 cell model. World Journal of Gastroenterology 15(16): 1977-1984, 2009

In vitro interactions between calcium, zinc, copper and iron in milk- and soy-based infant formulas / Interacciones in vitro entre calcio, cinc, cobre e hierro en formulas de base lactea y de soja para lactantes. Food Science and Technology International 6(1): 25-31, 2000

Calcium, iron, zinc, copper, manganese and selenium concentrations in typical hospital diets. Forum of Nutrition 56: 56-59, 2003

Aluminum and manganese tolerance on wheat (Triticum aestivum L.) cultivars. IV. Manganese tolerance as related to P, Ca, Mg, Fe, Mn, Zn, Cu Phosphorus, calcium, magnesium, iron, manganese, zinc, copper and Ca, Fe, and Mn Calcium, iron, manganese respectively in aerial parts and roots.10. 1980

The effect of dephytinisation on calcium, copper, iron, manganese and zinc absorption from a soy infant formula. JPGN 28(5): 595, 1999

Digestibility and retention of zinc, copper, manganese, iron, calcium, and phosphorus in pigs fed diets containing inorganic or organic minerals. Journal of Animal Science 92(8): 3407-3415, 2014

Upper limits of zinc, copper and manganese in infant formulas. Journal of Nutrition 119(12 Suppl): 1861-1864, 1989

Upper Limits of Zinc, Copper and Manganese in Infant Formulas. The Journal of Nutrition 119(Suppl_12): 1861-1864, 1989