Section 3
Chapter 2,581

Cloning and sequence analysis of the gene and cDNA encoding mouse spermidine/spermine N1-acetyltransferase - a gene uniquely regulated by polyamines and their analogs

Fogel Petrovic, M.; Kramer, D.L.; Ganis, B.; Casero, R.A.J.; Porter, C.W.

Biochimica et Biophysica Acta, Gene Structure and Expression 1216(2): 255-264


DOI: 10.1016/0167-4781(93)90152-4
Accession: 002580308

Download citation:  

The polyamine catabolizing enzyme, spermidine/spermine N1-acetyltransferase (diamine N-acetyltransferase) (SSAT), has been implicated as a critical determinant of polyamine pool maintenance. Mouse LA-4 lung adenoma cells treated with either spermine or the spermine analogue, N1,N12-bis(ethyl)spermine, produced a 2.3 and 6.5-fold increase, respectively, in SSAT mRNA.

PDF emailed within 0-6 h: $19.90