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Demonstration of the stability of freeze dried Brucella melitensis Rev. 1 and Brucella abortus S19 vaccines at different temperatures


, : Demonstration of the stability of freeze dried Brucella melitensis Rev. 1 and Brucella abortus S19 vaccines at different temperatures. Pendik Veteriner Mikrobiyoloji Dergisi 26(1): 45-54

Lyophilized full-dose B. melitensis Rev. 1 (1.7+or-0.601 x 109), reduced-dose B. melitensis Rev. 1 (5.9+or-0.875 x 109) and full-dose B. abortus S19 vaccines (50+or-7, 430 x 109) produced in fermenters in a liquid medium were maintained at five different storage temperatures (-20 degrees C, -10 degrees C, +4 degrees C, +20 degrees C and +37 degrees C) for 52 weeks and their viability determined periodically.

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