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Derivation of single-locus relationship coefficients conditional on marker information


, : Derivation of single-locus relationship coefficients conditional on marker information. Tag. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik 88(5): 548-556

The coefficient of relationship is defined as the correlation between the additive genetic values of two individuals. This coefficient can be defined specifically for a single quantitative trait locus (QTL) and may deviate considerably from the overall expectation if it is taken conditional on information from linked marker loci. Conditional halfsib correlations are derived under a simple genetic model with a biallelic QTL linked to a biallelic marker locus. The conditional relationship coefficients are shown to depend on the recombination rate between the marker and the QTL and the population frequency of the marker alleles, but not on parameters of the QTL, i.e. number and frequency of QTL alleles, degree of dominance etc., nor on the (usually unknown) QTL genotype of the sire. Extensions to less simplified cases (multiple alleles at the marker locus and the QTL, two marker loci flanking the QTL) are given. For arbitrary pedigrees, conditional relationship coefficients can also be derived from the conditional gametic covariance matrix suggested by Fernando and Grossman (1989). The connection of these two approaches is discussed. The conditional relationship coefficient can be used for marker-assisted genetic evaluation as well as for the detection of QTL and the estimation of their effects.

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Accession: 002590614

PMID: 24186109

DOI: 10.1007/BF01240917

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James Groves, 1928: On Charophyta collected by Mr Thomas Bates Blow, FLS, in Madagascar. Botanical Journal of the Linnean Society 48(320): 125-137

Braunlich, K.B.lcic, I., 1976: Factors affecting the utilization of vitamins in feed mixes. Krmiva 18 (2) 33-36

Kalninia, M.; Klegeris, I., 1978: Prospects of a dispatching service at the Latvian Agricultural Academy. Trudy 39) 23-28

Legendre, R., 1967: A propos de lenigmatique Gallieniella mygloides J Millot, 1947, type de ia nouvelle familie des Gallieniellidae Araneae, Dionychia. Cr hebd Seanc Acad Sei Paris, 265D 796-799

Kopetzky, M.T.; Maselli, R.; Ellis, E.F., 1974: Pulmonary function studies with simple equipment in 323 normal children. Journal of Allergy and Clinical Immunology 53(1): 1-8

Naumov, Y.N.; Hogan, K.T.; Naumova, E.N.; Pagel, J.T.; Gorski, J., 1998: A class I MHC-restricted recall response to a viral peptide is highly polyclonal despite stringent CDR3 selection: implications for establishing memory T cell repertoires in "real-world" conditions. In this study, we analyze the recall response to influenza A matrix peptide M1(58-66) restricted by HLA-A2 in one individual and find a strict CDR3 selection as well as a high degree of polyclonality. The TCR beta-chain repertoire of memory T cell...

Sansores, R.H.; Valdelamar, F.R.; Giraldo, F.L.; Ramirez-Venegas, A.; Villalba-Caloca, J., 1999: Impact of a gallery of posters on quitting smoking. Tobacco Control 7(4): 338-339

Villar, H.V.; Johnson, D.G.; Lynch, P.J.; Pond, G.D.; Smith, P.H., 1981: Pattern of immunoreactive glucagon in portal, arterial and peripheral plasma before and after removal of glucagonoma. Gel fractionation of portal, arterial and peripheral plasma glucagon levels was performed before and after the successful removal of a glucagonoma. A 47 year old woman had symptoms of dermatitis, weight loss, anemia and diabetes mellitus over a 16...

Kagaruki L.K., 1991: Tick acari ixodidae resistance to organochlorine acaricides in tanzania. Various species of ticks collected from different regions of Tanzania were tested for susceptibility to organochlorine (OC) acaricides between 1976 and 1987 using gamma HCH (lindane) and dieldrin as standard test chemicals. Of 189 strains tested,...

Eggins H.O.W.; Coursey D.G., 1968: The industrial significance of the bio deterioration of oilseeds. International Biodeterioration Bulletin 4(1): 29-38