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Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens

Steel, C.; Guinea, A.; McCarthy, J.S.; Ottesen, E.A.

Lancet 343(8902): 890-893

1994


ISSN/ISBN: 0140-6736
PMID: 7908359
DOI: 10.1016/s0140-6736(94)90009-4
Accession: 002649566

To identify long-term effects of prenatal exposure to maternal filarial-parasite infection, the authors assessed lymphocyte responses in 21 Polynesian children born 17-19 years previously to mothers diagnosed as being microfilaraemic or infection-free. All children lived on an island endemic for Wuchereria bancrofti filariasis but were free from infection at the time of study.

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