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Production of monoclonal antibodies with distinct neutralizing activity against virulent and the attenuated Bartha strain of Aujeszky's disease virus



Production of monoclonal antibodies with distinct neutralizing activity against virulent and the attenuated Bartha strain of Aujeszky's disease virus



Revista de Microbiologia 24(4): 222-227



Three monoclonal antibodies (MoAbs) with in vitro neutralizing activity against virulent Aujeszky virus (ADV) were produced. MoAbs 2E9 and 1H1 neutralized the virus only in the presence of exogenous complement, whereas MoAb G4 neutralized the virus in the absence of complement. However, none of the MoAbs were able to neutralize the naturally attenuated Bartha strain of ADV even in the presence of complement.

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