EurekaMag.com logo
+ Site Statistics
References:
53,517,315
Abstracts:
29,339,501
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The SAG2 antigen of Toxoplasma gondii and the 31-kDa surface antigen of Sarcocystis muris share similar sequence features



The SAG2 antigen of Toxoplasma gondii and the 31-kDa surface antigen of Sarcocystis muris share similar sequence features



Parasitology Research 81(5): 444-445



In the search for similar cysteine distribution patterns among surface antigens of members of the phylum of Apicomplexa, we found a resemblance between TgSAG2, a 22-kDa surface antigen of Toxoplasma gondii, and the C-terminal half of a 31-kDa surface antigen of Sarcocystis muris, SmSAG1. The overall degree of similarity is low, corresponding to 28% of identity in the 146 amino acids aligned. However, the conservative spacing between the cysteine residues suggest that this similarity might have functional implications. The described amino acid similarity provides a new clue to the molecular relationship between two closely related coccidian parasites.

(PDF 0-2 workdays service: $29.90)

Accession: 002709379

Download citation: RISBibTeXText

PMID: 7501647



Related references

Structural and functional characterization of SporoSAG: a SAG2-related surface antigen from Toxoplasma gondii. Journal of Biological Chemistry 285(16): 12063-12070, 2010

Analysis of Toxoplasma gondii surface antigen 2 gene (SAG2). Relevance of genotype I in clinical toxoplasmosis. Molecular Biology Reports 37(6): 2927-2933, 2010

Characterisation of a truncated Toxoplasma gondii surface antigen 2 (SAG2) secreted by the methylotrophic yeast Pichia pastoris. Tropical Biomedicine 23(2): 186-193, 2007

Characterisation of a truncated Toxoplasma gondii surface antigen 2 (SAG2) secreted by the methylotrophic yeast Pichia pastoris. Tropical Biomedicine 23(2): 186-193, 2006

Characterization of secreted recombinant Toxoplasma gondii surface antigen 2 (SAG2) heterologously expressed by the yeast Pichia pastoris. Biotechnology Letters 30(4): 611-618, 2007

Toxoplasma gondii: serological characterization and immunogenicity of recombinant surface antigen 2 (SAG2) expressed in the yeast Pichia pastoris. Experimental Parasitology 119(3): 373-378, 2008

Application and expression of Toxoplasma gondii surface antigen 2 (SAG2) and rhoptry protein 2 (ROP2) from recombinant Escherichia coli strain. Transactions of the Royal Society of Tropical Medicine and Hygiene 106(6): 356-362, 2012

Prime and boost immunization with influenza and adenovirus encoding the Toxoplasma gondii surface antigen 2 (SAG2) induces strong protective immunity. Vaccine 28(18): 3247-3256, 2010

Use of a recombinant antigen, SAG2, expressed as a glutathione-S-transferase fusion protein to immunize mice against Toxoplasma gondii. Parasitology Research 83(1): 6-9, 1997

Cloning, expression, and cDNA sequence of surface antigen P22 from Toxoplasma gondii. Molecular and Biochemical Parasitology, 431: 97-106, 1990

Cloning expression and complementary dna sequence of surface antigen p22 from toxoplasma gondii. Molecular & Biochemical Parasitology 43(1): 97-106, 1990

A new Toxoplasma gondii chimeric antigen containing fragments of SAG2, GRA1, and ROP1 proteins-impact of immunodominant sequences size on its diagnostic usefulness. Parasitology Research 114(9): 3291-3299, 2016

Structural characterization of the bradyzoite surface antigen (BSR4) from Toxoplasma gondii, a unique addition to the surface antigen glycoprotein 1-related superfamily. Journal of Biological Chemistry 284(14): 9192-9198, 2009

Sekuen Gen Surface Antigen-1 dan Bradizoit Antigen-1 Takizoit Toxoplasma gondii sebagai Kandidat Pemindai DNA. 2013