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Bayesian and residual maximum likelihood statistical gene mapping






Animal Biotechnology 8(1): 47-54

Bayesian and residual maximum likelihood statistical gene mapping

Residual Maximum Likelihood and Bayesian methods for statistical gene mapping in livestock were derived and applied to simulated half-sib designs. REML was robust to the number of QTL alleles, and Bayesian analysis permitted to fit different QTL models. Single QTLs explaining at least 12.5% of additive genetic variance were detected with power of .5 or higher. Two linked QTLs were detected when 20cM (40cM) apart and jointly accounting for 50% (25%) of additive genetic variance.

Accession: 002763170

DOI: 10.1080/10495399709525866

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