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Beta-carotene increases lung cancer incidence in cigarette smokers






Nutrition reviews 54(6): 178-180

Beta-carotene increases lung cancer incidence in cigarette smokers

Clinical trials were designed to validate the protective effect of beta-carotene in populations of cigarette smokers at high risk for lung cancer development. Strikingly, an increase in lung cancer resulted following beta-carotene supplementation in two separate studies in Finland and the United States. These trials were conducted without any evidence that beta-carotene prevents lung cancer in animal models.

Accession: 002763982

PMID: 8810825

DOI: 10.1111/j.1753-4887.1996.tb03926.x

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