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Characterization of mRNA expression of prostaglandin F2 alpha receptor in the bovine corpora lutea



Characterization of mRNA expression of prostaglandin F2 alpha receptor in the bovine corpora lutea



Journal of Reproduction and Development 42(Suppl): 64-66



A full length cDNA clone for PGF2 alpha receptors was isolated from a bovine corpus luteum library. The clone encoded a protein of 362 amino acid residues, with 7 potential transmembrane domains. The receptor protein was shown to be coupled to phosphoinositide metabolism in cDNA-transfected CHO cells. RNA blot analyses demonstrated that PGF2 alpha receptor mRNAs were abundantly expressed in the ovary, especially in large luteal cells.

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Accession: 002775772

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