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Comparison of rabbit monospecific anti-Brucella antisera with mouse anti-Brucella monoclonal antibodies

Comparison of rabbit monospecific anti-Brucella antisera with mouse anti-Brucella monoclonal antibodies

Archivos de Medicina Veterinaria 27(extraordinar): 131-137

Brucella abortus biovars 1-7 and 9 were agglutinated with dilutions of rabbit monospecific antisera (cross-absorbed and specific either for "A" or "M" antigens) or mouse monoclonal antibodies (not cross-absorbed, YsT9-3 with "A" specificity for B. abortus 1119-3 O-polysaccharide and Bm-15 with "M" specificity for B. melitensis 16M OPS). Observed similarities were that both rabbit anti-"A" antiserum and mouse monoclonal YsT9-3 antibody agglutinated biovars 1-3 and 6 but not biovars 4, 5 and 9.

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