+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of dietary corticosterone on mononuclear cells proliferation to mitogen in spleen and thymus of broiler chicks

Animal Science & Technology 67(2): 160-164

Effect of dietary corticosterone on mononuclear cells proliferation to mitogen in spleen and thymus of broiler chicks

Proliferative responses of mononuclear cell (MNC) in spleen and thymus to concanavalin A were investigated in chicks fed diets supplemented with 0 or 10 ppm corticosterone ad libitum for 10 days. When autologous serum was added to the culture medium at 5% of final volume, dietary corticosterone reduced the proliferative response of MNC in thymus, but not in spleen. The mitogenic response of splenocyte MNC obtained from the control-chicks was reduced by the addition of the serum obtained from chicks fed corticosterone, but the response of splenocyte MNC from chicks fed corticosterone did not differ from that of the control, regardless of serum sources. The results suggest that dietary corticosterone efficiently reduces the proliferative response of MNC in thymus to Con A rather than those in spleen. and may not impair, at least, capacity of Con A induced proliferative response of splenocyte in male broilers.

Accession: 002811715

Related references

Takimoto, T.; Sato, K.; Akiba, Y.; Takahashi, K., 2006: Effect of astaxanthin from Phaffia rhodozyma on T cell population and responsiveness to mitogen in splenic mononuclear cells of male broiler chicks. Chicks, 1-week-old, were fed ad libitum diets containing 0, 20 or 100 ppm Ax for 7 days. It was observed that Ax decreased the percentage of CD3-positive cells, an indicator of the T cell population in splenic lymphocytes. Diet with 20 ppm Ax decr...

Bartov, I.; Jensen, L.S.; Veltmann, J.R., 1980: Effect of dietary protein and fat levels on fattening of corticosterone-injected broiler chicks. The effect of dietary composition on fattening of cotricosterone-injected broilers was studied with Hubbard male chicks. Corticosterone was injected daily from 26 days of age during 9 days at a concentration of 600 micrograms/bird/day. Dietary ene...

Hayashi, R.M.; Kuritza, L.N.; Lourenco, M.C.; Miglino, L.B.; Pickler, L.; Rocha, C.; Maiorka, A.; Santin, E., 2013: Hatch window on development of intestinal mucosa and presence of CD3-positive cells in thymus and spleen of broiler chicks. Different periods of hatching, called hatch windows, occur inside the same hatchery and birds’ development could be affected by this. This study evaluated morphology of the intestinal mucosa and gizzard, and the presence of CD3+ cells in thy...

Kafri, I.R.sebrough, R.; Mcmurtry, J.; Steele, N., 1986: Effect of corticosterone (C) and dietary ascorbic acid (AA) on growth, feed consumption and lipid metabolism in broiler chicks. Poultry science5(1): 67

Kafri I.; Rosebrough R.W.; Mcmurtry J.P.; Steele N.C., 1986: Effect of corticosterone and dietary ascorbic acid on growth feed consumption and lipid metabolism in broiler chicks. Poultry Science 65(SUPPL 1): 67

Ali, N.A.; Lüdtke, J.; Pilgrim, H.; Lindequist, U., 1996: Inhibition of chemiluminescence response of human mononuclear cells and suppression of mitogen-induced proliferation of spleen lymphocytes of mice by hispolon and hispidin. The effects of two phenolic compounds, hispolon and hispidin isolated from fruit bodies of the basidiomycete Inonotus hispidus (Bull. ex Fr.) Karst, were investigated on the chemiluminescence response by LPS- or zymosan-activated human mononuclear...

Kutlu, H.R.; Forbes, J.M., 1994: Responses of broiler chicks to dietary ascorbic acid and corticosterone. British Poultry Science 35(1): 184-186

Weindruch, R.; Lane, M.A.; Ingram, D.K.; Ershler, W.B.; Roth, G.S., 1997: Dietary restriction in rhesus monkeys: lymphopenia and reduced mitogen-induced proliferation in peripheral blood mononuclear cells. Dietary restriction (DR) markedly extends mean and maximal life span, and retards the rate of biological aging in rodent models; however, it is unknown if these results occur in primate species. The purpose of the current study was to investigate...

Nikolic L.; Radujkov Z.; Borota R., 1979: Effect of bovine spleen chalone ultra filtration fractions on the proliferation of rat spleen thymus and bone marrow cells in vitro. Acta Biologiae et Medicinae Experimentalis SUPPL(1): 202-203

D'Amato, J.L.; Humphrey, B.D., 2010: Dietary arginine levels alter markers of arginine utilization in peripheral blood mononuclear cells and thymocytes in young broiler chicks. Arginine is an essential amino acid in Aves and is also an important substrate for the immune system. Dietary Arg in avian diets must be sufficient to not only support growth but also immunity. To better understand Arg needs for immunity, 2 experi...