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Endocrine regulation of reproductive function in fertile, subfertile and infertile stallions



Endocrine regulation of reproductive function in fertile, subfertile and infertile stallions



Reproduction in Domestic Animals 30(4): 245-250



The specific nature and relative contribution of the various factors involved in the endocrine/paracrine/autocrine control of reproductive function in normal stallions are not well defined nor have they been elucidated in the idiopathic subfertile/infertile stallion. Over the last 9 years, our laboratory has been engaged in characterizing the hypothalamic-pituitary-testicular axis (BPT) in fertile, subfertile (idiopathic oligospermia) and infertile (idiopathic azoospermia) stallions. Our studies have not only identified endocrine factors and mechanisms important for normal reproductive function, but they have demonstrated specific hormonal alterations in pituitary and testicular function between fertile, subfertile and infertile stallions. Recent evidence suggests that the primary defect is at the level of the testes. The nature of the dysfunction does not appear to involve changes in LH receptor binding kinetics but may be related to post-receptor mechanisms.

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Accession: 002827955

Download citation: RISBibTeXText

DOI: 10.1111/j.1439-0531.1995.tb00154.x



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