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Expression of the envelope glycoprotein E1 of classical swine fever virus by pseudorabies virus vector strains does not affect the in vitro replication of these vector viruses in porcine peripheral blood mononuclear cells



Expression of the envelope glycoprotein E1 of classical swine fever virus by pseudorabies virus vector strains does not affect the in vitro replication of these vector viruses in porcine peripheral blood mononuclear cells



Immunobiology of viral infections Proceedings 3rd Congress of the European Society for Veterinary Virology Interlaken, Switzerland, 4-7 September 1994: 74-78



The ability of Aujeszky virus (ADV) to replicate in vitro in porcine peripheral blood mononuclear cells (PBMC), and whether the expression of the envelope glycoprotein E1 (E1) of classical swine fever virus (CSFV) by non-virulent and virulent ADV vector strains changed this replication, were investigated. The non-virulent ADV vector strain was attenuated by inactivation of the genes encoding glycoprotein E (gE) and thymidine kinase (TK).

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