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Identification of bovine decorin in the fetal bovine rumen






Journal of Veterinary Medical Science 59(2): 121-123

Identification of bovine decorin in the fetal bovine rumen

Immunohistochemical localization of bovine decorin was examined with its biological analysis in the fetal bovine rumen. By immunohistochemical staining, monoclonal antibody (mAb) 2B6, which recognizes chondroitin 4-sulfate and/or dermatan sulfate (DS), reacted specifically to the lower mesenchymal region in the developing ruminal wall. Biochemical analysis of the extract from the developing rumen revealed that the molecule detected immunohistochemically by mAb 2B6 was small DS proteoglycan, bovine decorin. These results support the view that bovine decorin is involved in organization of the fetal bovine ruminal mesenchyme as a collagenous tissue.

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Accession: 002863347

PMID: 9070984

DOI: 10.1292/jvms.59.121



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