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Malaria cytoadherence: binding sites for an anti-adhesive antibody on Plasmodium falciparum-infected erythrocytes

, : Malaria cytoadherence: binding sites for an anti-adhesive antibody on Plasmodium falciparum-infected erythrocytes. Annals of Tropical Medicine and Parasitology 89(6): 685-686

The number of 1C4 molecules (a MAb which inhibits the binding of Plasmodium falciparum-infected erythrocytes to C32 amelanotic melanoma cells) that could potentially bind to the surface of infected erythrocytes was determined using an indirect method involving 125I-protein-A to detect the bound IgG. The mean number of 1C4 molecules which bound was calculated as 3089/infected erythrocyte.

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