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Malaria diagnosis by quantitative buffy coat technique



Malaria diagnosis by quantitative buffy coat technique



Medical Journal of Malaysia 51(2): 227-231



The QBC (quantitative buffy coat) method is a rapid diagnostic test for malaria based on acridine orange staining of centrifuged parasites in a microhaematocrit tube. The QBC tube method was compared with conventional blood film examination in the diagnosis of malaria in a double-blind study in 3 population groups. When compared with the thick blood smear in 318 hospital patients clinically suspected of having malaria, the QBC method showed 96.77% sensitivity and 98.73% specificity.

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