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Oxidative stress and ascorbate in relation to risk for cataract and age-related maculopathy

, : Oxidative stress and ascorbate in relation to risk for cataract and age-related maculopathy. Vitamin C in health and disease: 231-264

The prevalence and clinical features of cataracts and age-related macular degeneration (AMD) are outlined. The associations between cataract and exposure to high-intensity light, oxidation, smoking, and failure of primary and secondary defense systems are discussed. Dietary ascorbate intake has been shown to be related to eye tissue ascorbate levels. Studies on the association between cataract and antioxidant nutrients, including vitamin C, are reviewed.

Accession: 002914134

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Related references

Taylor, A.; Nowell, T., 1997: Oxidative stress and antioxidant function in relation to risk for cataract. Advances in Pharmacology 38: 515-536

Klein, R.; Klein, B.E.; Jensen, S.C.; Moss, S.E.; Cruickshanks, K.J., 1994: The relation of socioeconomic factors to age-related cataract, maculopathy, and impaired vision. The Beaver Dam Eye Study. Purpose: To investigate the relations between socioeconomic factors and the prevalence of age-related cataract, maculopathy, and visual impairment. Methods: A population-based sample of 4926 people 43 to 86 years of age was examined from 1988 to 1...

Smirnoff, N.; Pallanca, J.E., 1996: Ascorbate metabolism in relation to oxidative stress. Biochemical Society Transactions 24(2): 472-478

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