+ Translate

Pain-related behaviour following sodium urate arthritis is expressed in decerebrate chickens

, : Pain-related behaviour following sodium urate arthritis is expressed in decerebrate chickens. Physiology & Behavior 62(3): 581-584

The role of the telencephalon in pain-related behaviour in arthritis was investigated by measuring pain-coping behaviour (one-legged standing, lameness, sitting) of birds following intra-articular injection of sodium urate crystals. Ten sham-operated and 10 decerebrate birds were injected with sodium urate into the left ankle joint 4 days after surgery, and their behaviour recorded during a 3-h period. Both groups of birds showed pain-coping behaviour, and there was no significant difference between the 2 groups of birds. These results suggest that the behaviours associated with tonic arthritic pain are organised in the brainstem.

Accession: 002914691

PMID: 9272667

DOI: 10.1016/s0031-9384(97)00164-9

Download PDF Full Text: Pain-related behaviour following sodium urate arthritis is expressed in decerebrate chickens

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Okuda K.; Nakahama H.; Miyakawa H.; Shima K., 1984: Arthritis induced in cat by sodium urate a possible animal model for tonic pain. An attempt was made to determine whether cats rendered arthritic by the injection of monosodium urate (MSU) crystals (rod-shaped 40-130 .mu.m length) into 1 knee joint capsule can be used as an animal model for tonic (chronic) pain. A limp and a d...

Matthies, B.K.; Franklin, K.B.J., 1992: Formalin pain is expressed in decerebrate rats but not attenuated by morphine. Subcutaneous injection of dilute formalin induces pain in humans and behaviors indicative of pain in animals. The formalin test, which is based on these observations, is now widely used as a model of pain produced by tissue injury, but the neural...

Murakami N.; Kariya K.; Aihara S.; Maeda S., 1992: Analgesic effects of high molecular weight sodium hyaluronate on sodium urate induced knee pain in rats. Japanese Journal of Pharmacology 59(SUPPL 1): 416P

Gomarasca, P., 1976: Fentiazac in arthritis due to sodium urate. Bollettino Chimico Farmaceutico 115(11): 774-785

Hüttl, S.; Hüttlová, O., 1972: Sodium urate crystals in the diagnosis of uric arthritis. Beitrage Zur Rheumatologie 18: 35-39

Suttenfield, F.D., 1962: Arthritis after intrasynovial injection of sodium urate crystals. Lancet 2(7270): 1380-1381

Nakahama H., 1985: Modeling of inflammatory pain by sodium urate. Infection Inflammation & Immunity 15(4): 233-240

Faires, J.S.; Mccarty, D.J., 1962: Acute arthritis in man and dog after intrasynovial injection of sodium urate crystals. The intrasynovial injection of sodium-urate crystals in man and dog induced an acute inflammatory response which resembled gouty arthritis. They play a prominent role in the pathogenesis of the acute gout.

Bonnet, C.S.; Williams, A.S.; Gilbert, S.J.; Harvey, A.K.; Evans, B.A.; Mason, D.J., 2015: AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Synovial fluid glutamate concentrations increase in arthritis. Activation of kainate (KA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors (GluRs) increase interleukin-6 (IL-6) release and cause arthritic pain,...

Floersheim, G.L.; Brune, K.; Seiler, K., 1973: Colchicine in avian sodium urate and calcium pyrophosphate microcrystal arthritis. Agents and Actions 3(1): 20-23