+ Translate

Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis

, : Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis. American Journal of Hematology 50(1): 60-62

We present a case of hemophagocytosis during infection with the intraerythrocytic protozoan Babesia microti in a 47-year-old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia.

Accession: 002914856

PMID: 7668227

DOI: 10.1002/ajh.2830500113

Download PDF Full Text: Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Basu, S.; Mohan, H.; Malhotra, H., 2001: Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of tuberculosis. We report here an unusual hematologic manifestation of tuberculosis. A 40 year old male presented with pancytopenia due to hemophagocytic syndrome. Further investigations revealed he had tuberculosis.

Erdem, E.; Yıldırmak, Yıldız.; Günaydın, Nşen., 2011: Brucellosis presenting with pancytopenia due to hemophagocytic syndrome. Reaktif hemofagositik sendrom klinik olarak ateş, karaciğer ve dalak boyutlarında artış, pansitopeni ve pıhtılaşma bozuklukları; histolojik olarak da histiyosit ya da makrofajların artmış proliferasyon ve aktivasyonları ile karakteriz...

de Mello, R.Andrade.Bezerra.; Fonseca, E.; Brochado, M.; Quinaz, Jão.Manuel., 2010: Hemophagocytic Syndrome Associated with Hodgkin's Lymphoma First Presenting as Fever and Pancytopenia. Background. Hemophagocytic syndrome (HPS) is characterized by a hyperinflammatory reaction followed by alteration in cytotoxic function of Th1 lymphocytes and natural killer cells. We report a rare case of a patient that presented with fever and p...

Albaker, W., 2009: Acute Plasmodium vivax malaria presenting with pancytopenia secondary to hemophagocytic syndrome: case report and literature review. Pancytopenia as an initial manifestation of acute plasmodium vivax malaria is extremely rare and mainly reported with plasmodium falciparum. We report a 37- year old Nepali patient who recently came to Saudi Arabia and presented with a three-week...

Bhutani, V.; Dutta, U.; Das, R.; Singh, K., 2002: Hemophagocytic syndrome as the presenting manifestation of visceral leishmaniasis. Hemophagocytosis in visceral leishmaniasis is rare and usually mild. However, presentation as hemophagocytic syndrome is exceptionally rare. We report the case of a 28 years man who presented with fever, hepatosplenomegaly, pancytopenia, reactive...

Kobayashi, K-ichiro.; Usami, I.; Kubota, M.; Nishio, T., 2003: Acute vulvar ulceration as the main presenting manifestation of hemophagocytic syndrome. A 14-year-old female exhibited an acute vulvar ulcer during the course of hemophagocytic syndrome (HPS). The patient presented persistent high fever and a deep painful vulvar ulcer lasting for more than 2 weeks. Neither infection with sexually tra...

Grabas, M.; Darrieux, L.; Potier, Jérôme.; Safa, G., 2013: Hemophagocytic syndrome as the presenting manifestation of bacillary angiomatosis in a renal transplant recipient. Journal of the American Academy of Dermatology 67(5): E236-E237

Auerbach, M.; Haubenstock, A.; Soloman, G., 1986: Systemic babesiosis. Another cause of the hemophagocytic syndrome. Hemophagocytosis is a pathologic finding in a variety of infectious diseases associated with peripheral pancytopenia. In addition, hemophagocytosis is a prominent finding in malignant histiocytosis, a primary disorder of the monocyte-macrophage sy...

Boudes, P.; Balloul, E.; Sobel, A., 1989: Pancytopenia as the presenting manifestation of HIV infection in the elderly. Journal of the American Geriatrics Society 37(12): 1151-1152

Fiszbin, M.; L.J.unne, C.; Quint, L.; Hugues, F.C., 1998: Febrile pancytopenia in the course of AIDS: a hemophagocytic syndrome. La Revue de Medecine Interne 19(9): 673-675