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Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis


American Journal of Hematology 50(1): 60-62
Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis
We present a case of hemophagocytosis during infection with the intraerythrocytic protozoan Babesia microti in a 47-year-old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia.

Accession: 002914856

PMID: 7668227

DOI: 10.1002/ajh.2830500113

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