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Relationship of seborrheic dermatitis and Malassezia. An animal model of seborrheic dermatitis



Relationship of seborrheic dermatitis and Malassezia. An animal model of seborrheic dermatitis



Japanese Journal of Medical Mycology 36(4): 297-302



An experimental model for seborrhoeic dermatitis with M. furfur was developed using 16 male guineapigs, 5 C3H mice and 5 nude mice. M. furfur was inoculated without occlusion on the back and the ear. Clinical isolates of M. furfur were cultured in Dixon's broth. Seborrhoeic dermatitis-like lesions were observed on the back and the ear in some guineapigs after 7 d. Erythema appeared on 9 of 12 backs and 10 of 12 ears on the 25th day.

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Accession: 002942329

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DOI: 10.3314/jjmm.36.297


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